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Development of anti-membrane type 1-matrix metalloproteinase nanobodies as immunoPET probes for triple negative breast cancer imaging.
Mulero F, Oteo M, Garaulet G, Magro N, Rebollo L, Medrano G, Santiveri C, Romero E, Sellek RE, Margolles Y, Campos-Olivas R, Arroyo AG, Fernández LA, Morcillo MA, Martínez-Torrecuadrada JL. Mulero F, et al. Among authors: margolles y. Front Med (Lausanne). 2022 Nov 24;9:1058455. doi: 10.3389/fmed.2022.1058455. eCollection 2022. Front Med (Lausanne). 2022. PMID: 36507540 Free PMC article.
Nanobodies Protecting From Lethal SARS-CoV-2 Infection Target Receptor Binding Epitopes Preserved in Virus Variants Other Than Omicron.
Casasnovas JM, Margolles Y, Noriega MA, Guzmán M, Arranz R, Melero R, Casanova M, Corbera JA, Jiménez-de-Oya N, Gastaminza P, Garaigorta U, Saiz JC, Martín-Acebes MÁ, Fernández LÁ. Casasnovas JM, et al. Among authors: margolles y. Front Immunol. 2022 Apr 25;13:863831. doi: 10.3389/fimmu.2022.863831. eCollection 2022. Front Immunol. 2022. PMID: 35547740 Free PMC article.
Potent neutralization of clinical isolates of SARS-CoV-2 D614 and G614 variants by a monomeric, sub-nanomolar affinity nanobody.
Valenzuela Nieto G, Jara R, Watterson D, Modhiran N, Amarilla AA, Himelreichs J, Khromykh AA, Salinas-Rebolledo C, Pinto T, Cheuquemilla Y, Margolles Y, López González Del Rey N, Miranda-Chacon Z, Cuevas A, Berking A, Deride C, González-Moraga S, Mancilla H, Maturana D, Langer A, Toledo JP, Müller A, Uberti B, Krall P, Ehrenfeld P, Blesa J, Chana-Cuevas P, Rehren G, Schwefel D, Fernandez LÁ, Rojas-Fernandez A. Valenzuela Nieto G, et al. Among authors: margolles y. Sci Rep. 2021 Feb 8;11(1):3318. doi: 10.1038/s41598-021-82833-w. Sci Rep. 2021. PMID: 33558635 Free PMC article.
Selection of single domain antibodies from immune libraries displayed on the surface of E. coli cells with two β-domains of opposite topologies.
Salema V, Marín E, Martínez-Arteaga R, Ruano-Gallego D, Fraile S, Margolles Y, Teira X, Gutierrez C, Bodelón G, Fernández LÁ. Salema V, et al. Among authors: margolles y. PLoS One. 2013 Sep 23;8(9):e75126. doi: 10.1371/journal.pone.0075126. eCollection 2013. PLoS One. 2013. PMID: 24086454 Free PMC article.