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CCR5AS lncRNA variation differentially regulates CCR5, influencing HIV disease outcome.
Kulkarni S, Lied A, Kulkarni V, Rucevic M, Martin MP, Walker-Sperling V, Anderson SK, Ewy R, Singh S, Nguyen H, McLaren PJ, Viard M, Naranbhai V, Zou C, Lin Z, Gatanaga H, Oka S, Takiguchi M, Thio CL, Margolick J, Kirk GD, Goedert JJ, Hoots WK, Deeks SG, Haas DW, Michael N, Walker B, Le Gall S, Chowdhury FZ, Yu XG, Carrington M. Kulkarni S, et al. Among authors: margolick j. Nat Immunol. 2019 Jul;20(7):824-834. doi: 10.1038/s41590-019-0406-1. Epub 2019 Jun 17. Nat Immunol. 2019. PMID: 31209403 Free PMC article.
Genetic acceleration of AIDS progression by a promoter variant of CCR5.
Martin MP, Dean M, Smith MW, Winkler C, Gerrard B, Michael NL, Lee B, Doms RW, Margolick J, Buchbinder S, Goedert JJ, O'Brien TR, Hilgartner MW, Vlahov D, O'Brien SJ, Carrington M. Martin MP, et al. Among authors: margolick j. Science. 1998 Dec 4;282(5395):1907-11. doi: 10.1126/science.282.5395.1907. Science. 1998. PMID: 9836644
Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy.
Finzi D, Blankson J, Siliciano JD, Margolick JB, Chadwick K, Pierson T, Smith K, Lisziewicz J, Lori F, Flexner C, Quinn TC, Chaisson RE, Rosenberg E, Walker B, Gange S, Gallant J, Siliciano RF. Finzi D, et al. Among authors: margolick jb. Nat Med. 1999 May;5(5):512-7. doi: 10.1038/8394. Nat Med. 1999. PMID: 10229227
Effects of CCR5-Delta32, CCR2-64I, and SDF-1 3'A alleles on HIV-1 disease progression: An international meta-analysis of individual-patient data.
Ioannidis JP, Rosenberg PS, Goedert JJ, Ashton LJ, Benfield TL, Buchbinder SP, Coutinho RA, Eugen-Olsen J, Gallart T, Katzenstein TL, Kostrikis LG, Kuipers H, Louie LG, Mallal SA, Margolick JB, Martinez OP, Meyer L, Michael NL, Operskalski E, Pantaleo G, Rizzardi GP, Schuitemaker H, Sheppard HW, Stewart GJ, Theodorou ID, Ullum H, Vicenzi E, Vlahov D, Wilkinson D, Workman C, Zagury JF, O'Brien TR; International Meta-Analysis of HIV Host Genetics. Ioannidis JP, et al. Among authors: margolick jb. Ann Intern Med. 2001 Nov 6;135(9):782-95. doi: 10.7326/0003-4819-135-9-200111060-00008. Ann Intern Med. 2001. PMID: 11694103
441 results