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Sterically hindered complexes of platinum(II) with planar heterocyclic nitrogen donors. A novel complex with 1-methyl-cytosine has a spectrum of activity different from cisplatin and is able of overcoming acquired cisplatin resistance.
Margiotta N, Natile G, Capitelli F, Fanizzi FP, Boccarelli A, De Rinaldis P, Giordano D, Coluccia M. Margiotta N, et al. J Inorg Biochem. 2006 Nov;100(11):1849-57. doi: 10.1016/j.jinorgbio.2006.07.010. Epub 2006 Aug 3. J Inorg Biochem. 2006. PMID: 16959321
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