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Anti-mitochondrial autoantibodies in systemic lupus erythematosus and their association with disease manifestations.
Becker Y, Loignon RC, Julien AS, Marcoux G, Allaeys I, Lévesque T, Rollet-Labelle E, Benk-Fortin H, Cloutier N, Melki I, Eder L, Wagner É, Pelletier M, Hajj HE, Tremblay MÈ, Belleannée C, Hébert MJ, Dieudé M, Rauch J, Fortin PR, Boilard E. Becker Y, et al. Among authors: marcoux g. Sci Rep. 2019 Mar 14;9(1):4530. doi: 10.1038/s41598-019-40900-3. Sci Rep. 2019. PMID: 30872710 Free PMC article.
Autoantibodies in Systemic Lupus Erythematosus Target Mitochondrial RNA.
Becker Y, Marcoux G, Allaeys I, Julien AS, Loignon RC, Benk-Fortin H, Rollet-Labelle E, Rauch J, Fortin PR, Boilard E. Becker Y, et al. Among authors: marcoux g. Front Immunol. 2019 May 10;10:1026. doi: 10.3389/fimmu.2019.01026. eCollection 2019. Front Immunol. 2019. PMID: 31134086 Free PMC article.
Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation.
Boudreau LH, Duchez AC, Cloutier N, Soulet D, Martin N, Bollinger J, Paré A, Rousseau M, Naika GS, Lévesque T, Laflamme C, Marcoux G, Lambeau G, Farndale RW, Pouliot M, Hamzeh-Cognasse H, Cognasse F, Garraud O, Nigrovic PA, Guderley H, Lacroix S, Thibault L, Semple JW, Gelb MH, Boilard E. Boudreau LH, et al. Among authors: marcoux g. Blood. 2014 Oct 2;124(14):2173-83. doi: 10.1182/blood-2014-05-573543. Epub 2014 Jul 31. Blood. 2014. PMID: 25082876 Free PMC article.
Platelets release pathogenic serotonin and return to circulation after immune complex-mediated sequestration.
Cloutier N, Allaeys I, Marcoux G, Machlus KR, Mailhot B, Zufferey A, Levesque T, Becker Y, Tessandier N, Melki I, Zhi H, Poirier G, Rondina MT, Italiano JE, Flamand L, McKenzie SE, Cote F, Nieswandt B, Khan WI, Flick MJ, Newman PJ, Lacroix S, Fortin PR, Boilard E. Cloutier N, et al. Among authors: marcoux g. Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):E1550-E1559. doi: 10.1073/pnas.1720553115. Epub 2018 Jan 31. Proc Natl Acad Sci U S A. 2018. PMID: 29386381 Free PMC article.
Role of platelets and megakaryocytes in adaptive immunity.
Marcoux G, Laroche A, Espinoza Romero J, Boilard E. Marcoux G, et al. Platelets. 2021 Apr 3;32(3):340-351. doi: 10.1080/09537104.2020.1786043. Epub 2020 Jun 27. Platelets. 2021. PMID: 32597341 Review.
Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules.
Marcoux G, Laroche A, Hasse S, Bellio M, Mbarik M, Tamagne M, Allaeys I, Zufferey A, Lévesque T, Rebetz J, Karakeussian-Rimbaud A, Turgeon J, Bourgoin SG, Hamzeh-Cognasse H, Cognasse F, Kapur R, Semple JW, Hébert MJ, Pirenne F, Overkleeft HS, Florea BI, Dieude M, Vingert B, Boilard E. Marcoux G, et al. Blood. 2021 Dec 23;138(25):2607-2620. doi: 10.1182/blood.2020009957. Blood. 2021. PMID: 34293122 Free article.
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