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Oxidative stress promotes cytotoxicity in human cancer cell lines exposed to Escallonia spp. extracts.
Jara-Gutiérrez C, Mercado L, Paz-Araos M, Howard C, Parraga M, Escobar C, Mellado M, Madrid A, Montenegro I, Santana P, Murgas P, Jimenez-Jara C, González-Olivares LG, Ahumada M, Villena J. Jara-Gutiérrez C, et al. Among authors: mellado m. BMC Complement Med Ther. 2024 Jan 13;24(1):38. doi: 10.1186/s12906-024-04341-4. BMC Complement Med Ther. 2024. PMID: 38218817 Free PMC article.
In silico approaches to develop new phenyl-pyrimidines as glycogen synthase kinase 3 (GSK-3) inhibitors with halogen-bonding capabilities: 3D-QSAR CoMFA/CoMSIA, molecular docking and molecular dynamics studies.
Cabezas D, Mellado G, Espinoza N, Gárate JA, Morales C, Castro-Alvarez A, Matos MJ, Mellado M, Mella J. Cabezas D, et al. Among authors: mellado m. J Biomol Struct Dyn. 2023;41(22):13250-13259. doi: 10.1080/07391102.2023.2172457. Epub 2023 Jan 30. J Biomol Struct Dyn. 2023. PMID: 36718094
Synthesis of fluorescent chalcones, photophysical properties, quantitative structure-activity relationship and their biological application.
Mellado M, Sariego-Kluge R, Valdés-Navarro F, González C, Sánchez-González R, Pizarro N, Villena J, Jara-Gutierrez C, Cordova C, Bravo MA, Aguilar LF. Mellado M, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2023 Apr 15;291:122332. doi: 10.1016/j.saa.2023.122332. Epub 2023 Jan 6. Spectrochim Acta A Mol Biomol Spectrosc. 2023. PMID: 36652804
26 results