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Synthesis and acetylcholinesterase/butyrylcholinesterase inhibition activity of 4-amino-2, 3-diaryl-5, 6, 7, 8-tetrahydrofuro(and thieno)[2, 3-b]-quinolines, and 4-amino-5, 6, 7, 8, 9-pentahydro-2, 3-diphenylcyclohepta[e]furo(and thieno)-[2, 3-b]pyridines.
Marco JL, De Los Ríos C, Carreiras MC, Baños JE, Badia A, Vivas NM. Marco JL, et al. Arch Pharm (Weinheim). 2002 Jul;335(7):347-53. doi: 10.1002/1521-4184(200209)335:7<347::AID-ARDP347>3.0.CO;2-G. Arch Pharm (Weinheim). 2002. PMID: 12207285
Synthesis, biological evaluation and molecular modelling of diversely functionalized heterocyclic derivatives as inhibitors of acetylcholinesterase/butyrylcholinesterase and modulators of Ca2+ channels and nicotinic receptors.
Marco JL, de los Ríos C, García AG, Villarroya M, Carreiras MC, Martins C, Eleutério A, Morreale A, Orozco M, Luque FJ. Marco JL, et al. Bioorg Med Chem. 2004 May 1;12(9):2199-218. doi: 10.1016/j.bmc.2004.02.017. Bioorg Med Chem. 2004. PMID: 15080920
Recent approaches to novel anti-Alzheimer therapy.
Carreiras MC, Marco JL. Carreiras MC, et al. Among authors: marco jl. Curr Pharm Des. 2004;10(25):3167-75. doi: 10.2174/1381612043383421. Curr Pharm Des. 2004. PMID: 15544506 Review.
Novel tacrine derivatives that block neuronal calcium channels.
de los Ríos C, Marco JL, Carreiras MD, Chinchón PM, García AG, Villarroya M. de los Ríos C, et al. Among authors: marco jl. Bioorg Med Chem. 2002 Jun;10(6):2077-88. doi: 10.1016/s0968-0896(01)00378-9. Bioorg Med Chem. 2002. PMID: 11937366
ITH4012 (ethyl 5-amino-6,7,8,9-tetrahydro-2-methyl-4-phenylbenzol[1,8]naphthyridine-3-carboxylate), a novel acetylcholinesterase inhibitor with "calcium promotor" and neuroprotective properties.
Orozco C, de Los Rios C, Arias E, León R, García AG, Marco JL, Villarroya M, López MG. Orozco C, et al. Among authors: marco jl. J Pharmacol Exp Ther. 2004 Sep;310(3):987-94. doi: 10.1124/jpet.104.068189. Epub 2004 Apr 26. J Pharmacol Exp Ther. 2004. PMID: 15111641
125 results