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Glucose-6-Phosphate Dehydrogenase: Update and Analysis of New Mutations around the World.
Gómez-Manzo S, Marcial-Quino J, Vanoye-Carlo A, Serrano-Posada H, Ortega-Cuellar D, González-Valdez A, Castillo-Rodríguez RA, Hernández-Ochoa B, Sierra-Palacios E, Rodríguez-Bustamante E, Arreguin-Espinosa R. Gómez-Manzo S, et al. Int J Mol Sci. 2016 Dec 9;17(12):2069. doi: 10.3390/ijms17122069. Int J Mol Sci. 2016. PMID: 27941691 Free PMC article. Review.
The E104D mutation increases the susceptibility of human triosephosphate isomerase to proteolysis. Asymmetric cleavage of the two monomers of the homodimeric enzyme.
De La Mora-De La Mora I, Torres-Larios A, Mendoza-Hernández G, Enriquez-Flores S, Castillo-Villanueva A, Mendez ST, Garcia-Torres I, Torres-Arroyo A, Gómez-Manzo S, Marcial-Quino J, Oria-Hernández J, López-Velázquez G, Reyes-Vivas H. De La Mora-De La Mora I, et al. Biochim Biophys Acta. 2013 Dec;1834(12):2702-11. doi: 10.1016/j.bbapap.2013.08.012. Epub 2013 Sep 20. Biochim Biophys Acta. 2013. PMID: 24056040
Giardial triosephosphate isomerase as possible target of the cytotoxic effect of omeprazole in Giardia lamblia.
Reyes-Vivas H, de la Mora-de la Mora I, Castillo-Villanueva A, Yépez-Mulia L, Hernández-Alcántara G, Figueroa-Salazar R, García-Torres I, Gómez-Manzo S, Méndez ST, Vanoye-Carlo A, Marcial-Quino J, Torres-Arroyo A, Oria-Hernández J, Gutiérrez-Castrellón P, Enríquez-Flores S, López-Velázquez G. Reyes-Vivas H, et al. Antimicrob Agents Chemother. 2014 Dec;58(12):7072-82. doi: 10.1128/AAC.02900-14. Epub 2014 Sep 15. Antimicrob Agents Chemother. 2014. PMID: 25223993 Free PMC article.
The stability of G6PD is affected by mutations with different clinical phenotypes.
Gómez-Manzo S, Terrón-Hernández J, De la Mora-De la Mora I, González-Valdez A, Marcial-Quino J, García-Torres I, Vanoye-Carlo A, López-Velázquez G, Hernández-Alcántara G, Oria-Hernández J, Reyes-Vivas H, Enríquez-Flores S. Gómez-Manzo S, et al. Int J Mol Sci. 2014 Nov 17;15(11):21179-201. doi: 10.3390/ijms151121179. Int J Mol Sci. 2014. PMID: 25407525 Free PMC article.
The oxidative fermentation of ethanol in Gluconacetobacter diazotrophicus is a two-step pathway catalyzed by a single enzyme: alcohol-aldehyde Dehydrogenase (ADHa).
Gómez-Manzo S, Escamilla JE, González-Valdez A, López-Velázquez G, Vanoye-Carlo A, Marcial-Quino J, de la Mora-de la Mora I, Garcia-Torres I, Enríquez-Flores S, Contreras-Zentella ML, Arreguín-Espinosa R, Kroneck PM, Sosa-Torres ME. Gómez-Manzo S, et al. Int J Mol Sci. 2015 Jan 7;16(1):1293-311. doi: 10.3390/ijms16011293. Int J Mol Sci. 2015. PMID: 25574602 Free PMC article.
Structural effects of protein aging: terminal marking by deamidation in human triosephosphate isomerase.
de la Mora-de la Mora I, Torres-Larios A, Enríquez-Flores S, Méndez ST, Castillo-Villanueva A, Gómez-Manzo S, López-Velázquez G, Marcial-Quino J, Torres-Arroyo A, García-Torres I, Reyes-Vivas H, Oria-Hernández J. de la Mora-de la Mora I, et al. PLoS One. 2015 Apr 17;10(4):e0123379. doi: 10.1371/journal.pone.0123379. eCollection 2015. PLoS One. 2015. PMID: 25884638 Free PMC article.
Proton pump inhibitors drastically modify triosephosphate isomerase from Giardia lamblia at functional and structural levels, providing molecular leads in the design of new antigiardiasic drugs.
García-Torres I, de la Mora-de la Mora I, Marcial-Quino J, Gómez-Manzo S, Vanoye-Carlo A, Navarrete-Vázquez G, Colín-Lozano B, Gutiérrez-Castrellón P, Sierra-Palacios E, López-Velázquez G, Enríquez-Flores S. García-Torres I, et al. Biochim Biophys Acta. 2016 Jan;1860(1 Pt A):97-107. doi: 10.1016/j.bbagen.2015.10.021. Epub 2015 Oct 28. Biochim Biophys Acta. 2016. PMID: 26518348
Mutations of Glucose-6-Phosphate Dehydrogenase Durham, Santa-Maria and A+ Variants Are Associated with Loss Functional and Structural Stability of the Protein.
Gómez-Manzo S, Marcial-Quino J, Vanoye-Carlo A, Enríquez-Flores S, De la Mora-De la Mora I, González-Valdez A, García-Torres I, Martínez-Rosas V, Sierra-Palacios E, Lazcano-Pérez F, Rodríguez-Bustamante E, Arreguin-Espinosa R. Gómez-Manzo S, et al. Int J Mol Sci. 2015 Dec 2;16(12):28657-68. doi: 10.3390/ijms161226124. Int J Mol Sci. 2015. PMID: 26633385 Free PMC article.
45 results