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Design, synthesis, and biological evaluation of novel aminobisphosphonates possessing an in vivo antitumor activity through a gammadelta-T lymphocytes-mediated activation mechanism.
Simoni D, Gebbia N, Invidiata FP, Eleopra M, Marchetti P, Rondanin R, Baruchello R, Provera S, Marchioro C, Tolomeo M, Marinelli L, Limongelli V, Novellino E, Kwaasi A, Dunford J, Buccheri S, Caccamo N, Dieli F. Simoni D, et al. Among authors: marchetti p. J Med Chem. 2008 Nov 13;51(21):6800-7. doi: 10.1021/jm801003y. Epub 2008 Oct 21. J Med Chem. 2008. PMID: 18937434
Synthesis and biological activity of a novel class nicotinic acetylcholine receptors (nAChRs) ligands structurally related to anatoxin-a.
Simoni D, Rondanin R, Marchetti P, Rullo C, Baruchello R, Grisolia G, Barbato G, Giovannini R, Marchioro C, Capelli AM, Virginio C, Bozzoli A, Borea PA, Merighi S, Donati D. Simoni D, et al. Among authors: marchetti p. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5423-7. doi: 10.1016/j.bmcl.2011.06.127. Epub 2011 Jul 20. Bioorg Med Chem Lett. 2011. PMID: 21824774
Novel 3,4-isoxazolediamides as potent inhibitors of chaperone heat shock protein 90.
Baruchello R, Simoni D, Grisolia G, Barbato G, Marchetti P, Rondanin R, Mangiola S, Giannini G, Brunetti T, Alloatti D, Gallo G, Ciacci A, Vesci L, Castorina M, Milazzo FM, Cervoni ML, Guglielmi MB, Barbarino M, Foderà R, Pisano C, Cabri W. Baruchello R, et al. Among authors: marchetti p. J Med Chem. 2011 Dec 22;54(24):8592-604. doi: 10.1021/jm201155e. Epub 2011 Nov 23. J Med Chem. 2011. PMID: 22066525
4,5,6,7-Tetrahydro-isoxazolo-[4,5-c]-pyridines as a new class of cytotoxic Hsp90 inhibitors.
Baruchello R, Simoni D, Marchetti P, Rondanin R, Mangiola S, Costantini C, Meli M, Giannini G, Vesci L, Carollo V, Brunetti T, Battistuzzi G, Tolomeo M, Cabri W. Baruchello R, et al. Among authors: marchetti p. Eur J Med Chem. 2014 Apr 9;76:53-60. doi: 10.1016/j.ejmech.2014.01.056. Epub 2014 Jan 30. Eur J Med Chem. 2014. PMID: 24565573
1,445 results