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Islet Gene View-a tool to facilitate islet research.
Asplund O, Storm P, Chandra V, Hatem G, Ottosson-Laakso E, Mansour-Aly D, Krus U, Ibrahim H, Ahlqvist E, Tuomi T, Renström E, Korsgren O, Wierup N, Ibberson M, Solimena M, Marchetti P, Wollheim C, Artner I, Mulder H, Hansson O, Otonkoski T, Groop L, Prasad RB. Asplund O, et al. Among authors: marchetti p. Life Sci Alliance. 2022 Aug 10;5(12):e202201376. doi: 10.26508/lsa.202201376. Life Sci Alliance. 2022. PMID: 35948367 Free PMC article.
Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes.
Lyssenko V, Lupi R, Marchetti P, Del Guerra S, Orho-Melander M, Almgren P, Sjögren M, Ling C, Eriksson KF, Lethagen AL, Mancarella R, Berglund G, Tuomi T, Nilsson P, Del Prato S, Groop L. Lyssenko V, et al. Among authors: marchetti p. J Clin Invest. 2007 Aug;117(8):2155-63. doi: 10.1172/JCI30706. J Clin Invest. 2007. PMID: 17671651 Free PMC article. Clinical Trial.
Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion.
Lyssenko V, Nagorny CL, Erdos MR, Wierup N, Jonsson A, Spégel P, Bugliani M, Saxena R, Fex M, Pulizzi N, Isomaa B, Tuomi T, Nilsson P, Kuusisto J, Tuomilehto J, Boehnke M, Altshuler D, Sundler F, Eriksson JG, Jackson AU, Laakso M, Marchetti P, Watanabe RM, Mulder H, Groop L. Lyssenko V, et al. Among authors: marchetti p. Nat Genet. 2009 Jan;41(1):82-8. doi: 10.1038/ng.288. Epub 2008 Dec 7. Nat Genet. 2009. PMID: 19060908 Free PMC article.
Pleiotropic effects of GIP on islet function involve osteopontin.
Lyssenko V, Eliasson L, Kotova O, Pilgaard K, Wierup N, Salehi A, Wendt A, Jonsson A, De Marinis YZ, Berglund LM, Taneera J, Balhuizen A, Hansson O, Osmark P, Dunér P, Brøns C, Stancáková A, Kuusisto J, Bugliani M, Saxena R, Ahlqvist E, Kieffer TJ, Tuomi T, Isomaa B, Melander O, Sonestedt E, Orho-Melander M, Nilsson P, Bonetti S, Bonadonna R, Miccoli R, Delprato S, Marchetti P, Madsbad S, Poulsen P, Vaag A, Laakso M, Gomez MF, Groop L. Lyssenko V, et al. Among authors: marchetti p. Diabetes. 2011 Sep;60(9):2424-33. doi: 10.2337/db10-1532. Epub 2011 Aug 1. Diabetes. 2011. PMID: 21810601 Free PMC article.
A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets.
Marchetti P, Lupi R, Bugliani M, Kirkpatrick CL, Sebastiani G, Grieco FA, Del Guerra S, D'Aleo V, Piro S, Marselli L, Boggi U, Filipponi F, Tinti L, Salvini L, Wollheim CB, Purrello F, Dotta F. Marchetti P, et al. Diabetologia. 2012 Dec;55(12):3262-72. doi: 10.1007/s00125-012-2716-9. Epub 2012 Sep 11. Diabetologia. 2012. PMID: 22965295
1,444 results