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Divergent On-DNA Transformations from DNA-Linked Piperidones.
Ling X, Lu W, Miao L, Marcaurelle LA, Wang X, Ding Y, Lu X. Ling X, et al. Among authors: marcaurelle la. J Org Chem. 2022 Feb 18;87(4):1971-1976. doi: 10.1021/acs.joc.1c00670. Epub 2021 May 7. J Org Chem. 2022. PMID: 33960188
DNA-Encoded Library Hit Confirmation: Bridging the Gap Between On-DNA and Off-DNA Chemistry.
Xia B, Franklin GJ, Lu X, Bedard KL, Grady LC, Summerfield JD, Shi EX, King BW, Lind KE, Chiu C, Watts E, Bodmer V, Bai X, Marcaurelle LA. Xia B, et al. Among authors: marcaurelle la. ACS Med Chem Lett. 2021 Jun 3;12(7):1166-1172. doi: 10.1021/acsmedchemlett.1c00156. eCollection 2021 Jul 8. ACS Med Chem Lett. 2021. PMID: 34267887 Free PMC article.
Synthesis of stereochemically and skeletally diverse fused ring systems from functionalized C-glycosides.
Gerard B, Lee MD 4th, Dandapani S, Duvall JR, Fitzgerald ME, Kesavan S, Lowe JT, Marié JC, Pandya BA, Suh BC, O'Shea MW, Dombrowski M, Hamann D, Lemercier B, Murillo T, Akella LB, Foley MA, Marcaurelle LA. Gerard B, et al. Among authors: marcaurelle la. J Org Chem. 2013 Jun 7;78(11):5160-71. doi: 10.1021/jo4000916. Epub 2013 May 21. J Org Chem. 2013. PMID: 23692141 Free PMC article.
Synthesis and profiling of a diverse collection of azetidine-based scaffolds for the development of CNS-focused lead-like libraries.
Lowe JT, Lee MD 4th, Akella LB, Davoine E, Donckele EJ, Durak L, Duvall JR, Gerard B, Holson EB, Joliton A, Kesavan S, Lemercier BC, Liu H, Marié JC, Mulrooney CA, Muncipinto G, Welzel-O'Shea M, Panko LM, Rowley A, Suh BC, Thomas M, Wagner FF, Wei J, Foley MA, Marcaurelle LA. Lowe JT, et al. Among authors: marcaurelle la. J Org Chem. 2012 Sep 7;77(17):7187-211. doi: 10.1021/jo300974j. Epub 2012 Aug 10. J Org Chem. 2012. PMID: 22853001 Free PMC article.
Total synthesis of 6-deoxypladienolide D and Assessment of Splicing Inhibitory Activity in a Mutant SF3B1 cancer cell line.
Arai K, Buonamici S, Chan B, Corson L, Endo A, Gerard B, Hao MH, Karr C, Kira K, Lee L, Liu X, Lowe JT, Luo T, Marcaurelle LA, Mizui Y, Nevalainen M, O'Shea MW, Park ES, Perino SA, Prajapati S, Shan M, Smith PG, Tivitmahaisoon P, Wang JY, Warmuth M, Wu KM, Yu L, Zhang H, Zheng GZ, Keaney GF. Arai K, et al. Among authors: marcaurelle la. Org Lett. 2014 Nov 7;16(21):5560-3. doi: 10.1021/ol502556c. Epub 2014 Oct 26. Org Lett. 2014. PMID: 25376106
Photochemical C-H arylation of heteroarenes for DNA-encoded library synthesis.
Krumb M, Kammer LM, Badir SO, Cabrera-Afonso MJ, Wu VE, Huang M, Csakai A, Marcaurelle LA, Molander GA. Krumb M, et al. Among authors: marcaurelle la. Chem Sci. 2021 Dec 21;13(4):1023-1029. doi: 10.1039/d1sc05683b. eCollection 2022 Jan 26. Chem Sci. 2021. PMID: 35211268 Free PMC article.
Combinatorial carbohydrate chemistry.
Marcaurelle LA, Seeberger PH. Marcaurelle LA, et al. Curr Opin Chem Biol. 2002 Jun;6(3):289-96. doi: 10.1016/s1367-5931(02)00322-8. Curr Opin Chem Biol. 2002. PMID: 12023107 Review.
45 results