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KAP1 is an antiparallel dimer with a functional asymmetry.
Fonti G, Marcaida MJ, Bryan LC, Träger S, Kalantzi AS, Helleboid PJ, Demurtas D, Tully MD, Grudinin S, Trono D, Fierz B, Dal Peraro M. Fonti G, et al. Among authors: marcaida mj. Life Sci Alliance. 2019 Aug 19;2(4):e201900349. doi: 10.26508/lsa.201900349. Print 2019 Aug. Life Sci Alliance. 2019. PMID: 31427381 Free PMC article.
Btk SH2-kinase interface is critical for allosteric kinase activation and its targeting inhibits B-cell neoplasms.
Duarte DP, Lamontanara AJ, La Sala G, Jeong S, Sohn YK, Panjkovich A, Georgeon S, Kükenshöner T, Marcaida MJ, Pojer F, De Vivo M, Svergun D, Kim HS, Dal Peraro M, Hantschel O. Duarte DP, et al. Among authors: marcaida mj. Nat Commun. 2020 May 8;11(1):2319. doi: 10.1038/s41467-020-16128-5. Nat Commun. 2020. PMID: 32385234 Free PMC article.
Prolyl endopeptidase-like is a (thio)esterase involved in mitochondrial respiratory chain function.
Rosier K, McDevitt MT, Smet J, Floyd BJ, Verschoore M, Marcaida MJ, Bingman CA, Lemmens I, Dal Peraro M, Tavernier J, Cravatt BF, Gounko NV, Vints K, Monnens Y, Bhalla K, Aerts L, Rashan EH, Vanlander AV, Van Coster R, Régal L, Pagliarini DJ, Creemers JWM. Rosier K, et al. Among authors: marcaida mj. iScience. 2021 Nov 14;24(12):103460. doi: 10.1016/j.isci.2021.103460. eCollection 2021 Dec 17. iScience. 2021. PMID: 34888501 Free PMC article.
Discovery of a Selective Aurora A Kinase Inhibitor by Virtual Screening.
Kilchmann F, Marcaida MJ, Kotak S, Schick T, Boss SD, Awale M, Gönczy P, Reymond JL. Kilchmann F, et al. Among authors: marcaida mj. J Med Chem. 2016 Aug 11;59(15):7188-211. doi: 10.1021/acs.jmedchem.6b00709. Epub 2016 Jul 20. J Med Chem. 2016. PMID: 27391133
26 results