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Legacy data sharing to improve drug safety assessment: the eTOX project.
Sanz F, Pognan F, Steger-Hartmann T, Díaz C; eTOX; Cases M, Pastor M, Marc P, Wichard J, Briggs K, Watson DK, Kleinöder T, Yang C, Amberg A, Beaumont M, Brookes AJ, Brunak S, Cronin MTD, Ecker GF, Escher S, Greene N, Guzmán A, Hersey A, Jacques P, Lammens L, Mestres J, Muster W, Northeved H, Pinches M, Saiz J, Sajot N, Valencia A, van der Lei J, Vermeulen NPE, Vock E, Wolber G, Zamora I. Sanz F, et al. Among authors: marc p. Nat Rev Drug Discov. 2017 Dec;16(12):811-812. doi: 10.1038/nrd.2017.177. Epub 2017 Oct 13. Nat Rev Drug Discov. 2017. PMID: 29026211 Free article.
Generating Modeling Data From Repeat-Dose Toxicity Reports.
López-Massaguer O, Pinto-Gil K, Sanz F, Amberg A, Anger LT, Stolte M, Ravagli C, Marc P, Pastor M. López-Massaguer O, et al. Among authors: marc p. Toxicol Sci. 2018 Mar 1;162(1):287-300. doi: 10.1093/toxsci/kfx254. Toxicol Sci. 2018. PMID: 29155963 Free PMC article.
Value of shared preclinical safety studies - The eTOX database.
Briggs K, Barber C, Cases M, Marc P, Steger-Hartmann T. Briggs K, et al. Among authors: marc p. Toxicol Rep. 2014 Dec 18;2:210-221. doi: 10.1016/j.toxrep.2014.12.004. eCollection 2015. Toxicol Rep. 2014. PMID: 28962354 Free PMC article.
Ten simple rules to power drug discovery with data science.
Ferrero E, Brachat S, Jenkins JL, Marc P, Skewes-Cox P, Altshuler RC, Gubser Keller C, Kauffmann A, Sassaman EK, Laramie JM, Schoeberl B, Borowsky ML, Stiefl N. Ferrero E, et al. Among authors: marc p. PLoS Comput Biol. 2020 Aug 27;16(8):e1008126. doi: 10.1371/journal.pcbi.1008126. eCollection 2020 Aug. PLoS Comput Biol. 2020. PMID: 32853229 Free PMC article. No abstract available.
Coronary Artery Disease Polygenic Risk Score Identifies Patients at Higher Risk for Recurrent Cardiovascular Events in the CANTOS Trial.
Xu H, Hon C, Kaiser S, Serrano-Fernandez P, Hartmann N, Yates DP, Healey M, Gusev AI, Laramie JM, Kennedy S, Marc P, Ridker PM, Obeidat M, Beste MT, Svensson EC, Madar A. Xu H, et al. Among authors: marc p. Circ Genom Precis Med. 2021 Dec;14(6):e003440. doi: 10.1161/CIRCGEN.121.003440. Epub 2021 Oct 19. Circ Genom Precis Med. 2021. PMID: 34663088 No abstract available.
54 results