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SIRT1 regulates DNA damage signaling through the PP4 phosphatase complex.
Rasti G, Becker M, Vazquez BN, Espinosa-Alcantud M, Fernández-Duran I, Gámez-García A, Ianni A, Gonzalez J, Bosch-Presegué L, Marazuela-Duque A, Guitart-Solanes A, Segura-Bayona S, Bech-Serra JJ, Scher M, Serrano L, Shankavaram U, Erdjument-Bromage H, Tempst P, Reinberg D, Olivella M, Stracker TH, de la Torre C, Vaquero A. Rasti G, et al. Among authors: marazuela duque a. Nucleic Acids Res. 2023 Jul 21;51(13):6754-6769. doi: 10.1093/nar/gkad504. Nucleic Acids Res. 2023. PMID: 37309898 Free PMC article.
The tumor suppressor SirT2 regulates cell cycle progression and genome stability by modulating the mitotic deposition of H4K20 methylation.
Serrano L, Martínez-Redondo P, Marazuela-Duque A, Vazquez BN, Dooley SJ, Voigt P, Beck DB, Kane-Goldsmith N, Tong Q, Rabanal RM, Fondevila D, Muñoz P, Krüger M, Tischfield JA, Vaquero A. Serrano L, et al. Among authors: marazuela duque a. Genes Dev. 2013 Mar 15;27(6):639-53. doi: 10.1101/gad.211342.112. Epub 2013 Mar 6. Genes Dev. 2013. PMID: 23468428 Free PMC article.
SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-κB pathway.
Santos-Barriopedro I, Bosch-Presegué L, Marazuela-Duque A, de la Torre C, Colomer C, Vazquez BN, Fuhrmann T, Martínez-Pastor B, Lu W, Braun T, Bober E, Jenuwein T, Serrano L, Esteller M, Chen Z, Barceló-Batllori S, Mostoslavsky R, Espinosa L, Vaquero A. Santos-Barriopedro I, et al. Among authors: marazuela duque a. Nat Commun. 2018 Jan 9;9(1):101. doi: 10.1038/s41467-017-02586-x. Nat Commun. 2018. PMID: 29317652 Free PMC article.
Shikimic acid protects skin cells from UV-induced senescence through activation of the NAD+-dependent deacetylase SIRT1.
Martínez-Gutiérrez A, Fernández-Duran I, Marazuela-Duque A, Simonet NG, Yousef I, Martínez-Rovira I, Martínez-Hoyos J, Vaquero A. Martínez-Gutiérrez A, et al. Among authors: marazuela duque a. Aging (Albany NY). 2021 Apr 26;13(9):12308-12333. doi: 10.18632/aging.203010. Epub 2021 Apr 26. Aging (Albany NY). 2021. PMID: 33901008 Free PMC article.
A complex interplay between H2A.Z and HP1 isoforms regulates pericentric heterochromatin.
González J, Bosch-Presegué L, Marazuela-Duque A, Guitart-Solanes A, Espinosa-Alcantud M, Fernandez AF, Brown JP, Ausió J, Vazquez BN, Singh PB, Fraga MF, Vaquero A. González J, et al. Among authors: marazuela duque a. Front Cell Dev Biol. 2023 Nov 9;11:1293122. doi: 10.3389/fcell.2023.1293122. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 38020886 Free PMC article.