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FDA-approved carbonic anhydrase inhibitors reduce amyloid β pathology and improve cognition, by ameliorating cerebrovascular health and glial fitness.
Canepa E, Parodi-Rullan R, Vazquez-Torres R, Gamallo-Lana B, Guzman-Hernandez R, Lemon NL, Angiulli F, Debure L, Ilies MA, Østergaard L, Wisniewski T, Gutiérrez-Jiménez E, Mar AC, Fossati S. Canepa E, et al. Among authors: mar ac. Alzheimers Dement. 2023 Nov;19(11):5048-5073. doi: 10.1002/alz.13063. Epub 2023 Apr 26. Alzheimers Dement. 2023. PMID: 37186121
Inhibiting LXRα phosphorylation in hematopoietic cells reduces inflammation and attenuates atherosclerosis and obesity in mice.
Voisin M, Shrestha E, Rollet C, Nikain CA, Josefs T, Mahé M, Barrett TJ, Chang HR, Ruoff R, Schneider JA, Garabedian ML, Zoumadakis C, Yun C, Badwan B, Brown EJ, Mar AC, Schneider RJ, Goldberg IJ, Pineda-Torra I, Fisher EA, Garabedian MJ. Voisin M, et al. Among authors: mar ac. Commun Biol. 2021 Mar 26;4(1):420. doi: 10.1038/s42003-021-01925-5. Commun Biol. 2021. PMID: 33772096 Free PMC article.
Impulsivity is a heritable trait in rodents and associated with a novel quantitative trait locus on chromosome 1.
Jupp B, Pitzoi S, Petretto E, Mar AC, Oliver YP, Jordan ER, Taylor S, Atanur SS, Srivastava PK, Saar K, Hubner N, Sommer WH, Staehlin O, Spanagel R, Robinson ES, Schumann G, Moreno M, Everitt BJ, Robbins TW, Aitman TJ, Dalley JW. Jupp B, et al. Among authors: mar ac. Sci Rep. 2020 Apr 21;10(1):6684. doi: 10.1038/s41598-020-63646-9. Sci Rep. 2020. PMID: 32317713 Free PMC article.
Dopamine D2-like receptor stimulation blocks negative feedback in visual and spatial reversal learning in the rat: behavioural and computational evidence.
Alsiö J, Phillips BU, Sala-Bayo J, Nilsson SRO, Calafat-Pla TC, Rizwand A, Plumbridge JM, López-Cruz L, Dalley JW, Cardinal RN, Mar AC, Robbins TW. Alsiö J, et al. Among authors: mar ac. Psychopharmacology (Berl). 2019 Aug;236(8):2307-2323. doi: 10.1007/s00213-019-05296-y. Epub 2019 Jun 19. Psychopharmacology (Berl). 2019. PMID: 31218428 Free PMC article.
51 results