Maréchal E - Search Results

1

Integration and mining of malaria molecular, functional and pharmacological data: how far are we from a chemogenomic knowledge space?

Birkholtz LM, Bastien O, Wells G, Grando D, Joubert F, Kasam V, Zimmermann M, Ortet P, Jacq N, Saïdani N, Roy S, Hofmann-Apitius M, Breton V, Louw AI, Maréchal E. Birkholtz LM, et al. Among authors: marechal e. Malar J. 2006 Nov 17;5:110. doi: 10.1186/1475-2875-5-110. Malar J. 2006. PMID: 17112376 Free PMC article. Review.

2

Exploring functional genomics for drug target and therapeutics discovery in Plasmodia.

Birkholtz L, van Brummelen AC, Clark K, Niemand J, Maréchal E, Llinás M, Louw AI. Birkholtz L, et al. Among authors: marechal e. Acta Trop. 2008 Feb;105(2):113-23. doi: 10.1016/j.actatropica.2007.10.013. Epub 2007 Nov 12. Acta Trop. 2008. PMID: 18083131 Review.

3

Antimalarial drug discovery: in silico structural biology and rational drug design.

de Beer TA, Wells GA, Burger PB, Joubert F, Marechal E, Birkholtz L, Louw AI. de Beer TA, et al. Among authors: marechal e. Infect Disord Drug Targets. 2009 Jun;9(3):304-18. doi: 10.2174/1871526510909030304. Infect Disord Drug Targets. 2009. PMID: 19519484 Review.

4

Potential and limits of in silico target discovery - Case study of the search for new antimalarial chemotherapeutic targets.

Saïdani N, Grando D, Valadié H, Bastien O, Maréchal E. Saïdani N, et al. Among authors: marechal e. Infect Genet Evol. 2009 May;9(3):359-67. doi: 10.1016/j.meegid.2008.01.001. Epub 2008 Jan 15. Infect Genet Evol. 2009. PMID: 18294927 Review.

5

Construction of non-symmetric substitution matrices derived from proteomes with biased amino acid distributions.

Bastien O, Roy S, Maréchal E. Bastien O, et al. Among authors: marechal e. C R Biol. 2005 May;328(5):445-53. doi: 10.1016/j.crvi.2005.02.002. C R Biol. 2005. PMID: 15948633 Free article.

6

A configuration space of homologous proteins conserving mutual information and allowing a phylogeny inference based on pair-wise Z-score probabilities.

Bastien O, Ortet P, Roy S, Maréchal E. Bastien O, et al. Among authors: marechal e. BMC Bioinformatics. 2005 Mar 10;6:49. doi: 10.1186/1471-2105-6-49. BMC Bioinformatics. 2005. PMID: 15757521 Free PMC article.

7

Analysis of the compositional biases in Plasmodium falciparum genome and proteome using Arabidopsis thaliana as a reference.

Bastien O, Lespinats S, Roy S, Métayer K, Fertil B, Codani JJ, Maréchal E. Bastien O, et al. Among authors: marechal e. Gene. 2004 Jul 21;336(2):163-73. doi: 10.1016/j.gene.2004.04.029. Gene. 2004. PMID: 15246528

8

Evolution of biological sequences implies an extreme value distribution of type I for both global and local pairwise alignment scores.

Bastien O, Maréchal E. Bastien O, et al. Among authors: marechal e. BMC Bioinformatics. 2008 Aug 7;9:332. doi: 10.1186/1471-2105-9-332. BMC Bioinformatics. 2008. PMID: 18687111 Free PMC article.

9

Enhanced antimalarial activity of novel synthetic aculeatin derivatives.

Peuchmaur M, Saïdani N, Botté C, Maréchal E, Vial H, Wong YS. Peuchmaur M, et al. Among authors: marechal e. J Med Chem. 2008 Aug 28;51(16):4870-3. doi: 10.1021/jm8007322. Epub 2008 Aug 5. J Med Chem. 2008. PMID: 18680278

10

Discovery of compounds blocking the proliferation of Toxoplasma gondii and Plasmodium falciparum in a chemical space based on piperidinyl-benzimidazolone analogs.

Saïdani N, Botté CY, Deligny M, Bonneau AL, Reader J, Lasselin R, Merer G, Niepceron A, Brossier F, Cintrat JC, Rousseau B, Birkholtz LM, Cesbron-Delauw MF, Dubremetz JF, Mercier C, Vial H, Lopez R, Maréchal E. Saïdani N, et al. Among authors: marechal e. Antimicrob Agents Chemother. 2014 May;58(5):2586-97. doi: 10.1128/AAC.01445-13. Epub 2014 Feb 18. Antimicrob Agents Chemother. 2014. PMID: 24550329 Free PMC article.

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