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KAP1 is a new non-genetic vulnerability of malignant pleural mesothelioma (MPM).
Lorenzini E, Torricelli F, Zamponi R, Donati B, Manicardi V, Sauta E, Faria do Valle I, Reggiani F, Gugnoni M, Manzotti G, Fragliasso V, Vitale E, Piana S, Sancisi V, Ciarrocchi A. Lorenzini E, et al. Among authors: manzotti g. NAR Cancer. 2022 Jul 29;4(3):zcac024. doi: 10.1093/narcan/zcac024. eCollection 2022 Sep. NAR Cancer. 2022. PMID: 35910692 Free PMC article.
The biological effects of C/EBPalpha in K562 cells depend on the potency of the N-terminal regulatory region, not on specificity of the DNA binding domain.
Ferrari-Amorotti G, Mariani SA, Novi C, Cattelani S, Pecorari L, Corradini F, Soliera AR, Manzotti G, Fragliasso V, Zhang Y, Martinez RV, Lam EW, Guerzoni C, Calabretta B. Ferrari-Amorotti G, et al. Among authors: manzotti g. J Biol Chem. 2010 Oct 1;285(40):30837-50. doi: 10.1074/jbc.M110.128272. Epub 2010 Jul 20. J Biol Chem. 2010. PMID: 20659895 Free PMC article.
Phosphorylation of serine 21 modulates the proliferation inhibitory more than the differentiation inducing effects of C/EBPα in K562 cells.
Fragliasso V, Chiodo Y, Ferrari-Amorotti G, Soliera AR, Manzotti G, Cattelani S, Candini O, Grisendi G, Vergalli J, Mariani SA, Guerzoni C, Calabretta B. Fragliasso V, et al. Among authors: manzotti g. J Cell Biochem. 2012 May;113(5):1704-13. doi: 10.1002/jcb.24040. J Cell Biochem. 2012. PMID: 22212957 Free PMC article.
The p53 codon 72 Pro/Pro genotype identifies poor-prognosis neuroblastoma patients: correlation with reduced apoptosis and enhanced senescence by the p53-72P isoform.
Cattelani S, Ferrari-Amorotti G, Galavotti S, Defferrari R, Tanno B, Cialfi S, Vergalli J, Fragliasso V, Guerzoni C, Manzotti G, Soliera AR, Menin C, Bertorelle R, McDowell HP, Inserra A, Belli ML, Varesio L, Tweddle D, Tonini GP, Altavista P, Dominici C, Raschellà G, Calabretta B. Cattelani S, et al. Among authors: manzotti g. Neoplasia. 2012 Jul;14(7):634-43. doi: 10.1593/neo.12594. Neoplasia. 2012. PMID: 22904680 Free PMC article.
Inhibiting interactions of lysine demethylase LSD1 with snail/slug blocks cancer cell invasion.
Ferrari-Amorotti G, Fragliasso V, Esteki R, Prudente Z, Soliera AR, Cattelani S, Manzotti G, Grisendi G, Dominici M, Pieraccioli M, Raschellà G, Chiodoni C, Colombo MP, Calabretta B. Ferrari-Amorotti G, et al. Among authors: manzotti g. Cancer Res. 2013 Jan 1;73(1):235-45. doi: 10.1158/0008-5472.CAN-12-1739. Epub 2012 Oct 10. Cancer Res. 2013. PMID: 23054398 Free PMC article.
Cadherin-6 promotes EMT and cancer metastasis by restraining autophagy.
Gugnoni M, Sancisi V, Gandolfi G, Manzotti G, Ragazzi M, Giordano D, Tamagnini I, Tigano M, Frasoldati A, Piana S, Ciarrocchi A. Gugnoni M, et al. Among authors: manzotti g. Oncogene. 2017 Feb 2;36(5):667-677. doi: 10.1038/onc.2016.237. Epub 2016 Jul 4. Oncogene. 2017. PMID: 27375021
RUNX2 expression in thyroid and breast cancer requires the cooperation of three non-redundant enhancers under the control of BRD4 and c-JUN.
Sancisi V, Manzotti G, Gugnoni M, Rossi T, Gandolfi G, Gobbi G, Torricelli F, Catellani F, Faria do Valle I, Remondini D, Castellani G, Ragazzi M, Piana S, Ciarrocchi A. Sancisi V, et al. Among authors: manzotti g. Nucleic Acids Res. 2017 Nov 2;45(19):11249-11267. doi: 10.1093/nar/gkx802. Nucleic Acids Res. 2017. PMID: 28981843 Free PMC article.
88 results