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CRISPR-Cas9-based functional interrogation of unconventional translatome reveals human cancer dependency on cryptic non-canonical open reading frames.
Zheng C, Wei Y, Zhang P, Lin K, He D, Teng H, Manyam G, Zhang Z, Liu W, Lee HRL, Tang X, He W, Islam N, Jain A, Chiu Y, Cao S, Diao Y, Meyer-Gauen S, Höök M, Malovannaya A, Li W, Hu M, Wang W, Xu H, Kopetz S, Chen Y. Zheng C, et al. Among authors: manyam g. Nat Struct Mol Biol. 2023 Dec;30(12):1878-1892. doi: 10.1038/s41594-023-01117-1. Epub 2023 Nov 6. Nat Struct Mol Biol. 2023. PMID: 37932451 Free PMC article.
KPP: KEGG Pathway Painter.
Manyam G, Birerdinc A, Baranova A. Manyam G, et al. BMC Syst Biol. 2015;9 Suppl 2(Suppl 2):S3. doi: 10.1186/1752-0509-9-S2-S3. Epub 2015 Apr 15. BMC Syst Biol. 2015. PMID: 25879163 Free PMC article.
DNA Sequencing of Small Bowel Adenocarcinomas Identifies Targetable Recurrent Mutations in the ERBB2 Signaling Pathway.
Adam L, San Lucas FA, Fowler R, Yu Y, Wu W, Liu Y, Wang H, Menter D, Tetzlaff MT, Ensor J Jr, Manyam G, Arold ST, Huff C, Kopetz S, Scheet P, Overman MJ. Adam L, et al. Among authors: manyam g. Clin Cancer Res. 2019 Jan 15;25(2):641-651. doi: 10.1158/1078-0432.CCR-18-1480. Epub 2018 Oct 23. Clin Cancer Res. 2019. PMID: 30352910 Free PMC article.
ARID1A Mutation May Define an Immunologically Active Subgroup in Patients with Microsatellite Stable Colorectal Cancer.
Mehrvarz Sarshekeh A, Alshenaifi J, Roszik J, Manyam GC, Advani SM, Katkhuda R, Verma A, Lam M, Willis J, Shen JP, Morris J, Davis JS, Loree JM, Lee HM, Ajani JA, Maru DM, Overman MJ, Kopetz S. Mehrvarz Sarshekeh A, et al. Clin Cancer Res. 2021 Mar 15;27(6):1663-1670. doi: 10.1158/1078-0432.CCR-20-2404. Epub 2021 Jan 7. Clin Cancer Res. 2021. PMID: 33414133 Free PMC article.
Methylation-eQTL analysis in cancer research.
Liu Y, Baggerly KA, Orouji E, Manyam G, Chen H, Lam M, Davis JS, Lee MS, Broom BM, Menter DG, Rai K, Kopetz S, Morris JS. Liu Y, et al. Among authors: manyam g. Bioinformatics. 2021 Nov 18;37(22):4014-4022. doi: 10.1093/bioinformatics/btab443. Bioinformatics. 2021. PMID: 34117863 Free PMC article.
Targeting RAS Mutant Colorectal Cancer with Dual Inhibition of MEK and CDK4/6.
Sorokin AV, Kanikarla Marie P, Bitner L, Syed M, Woods M, Manyam G, Kwong LN, Johnson B, Morris VK, Jones P, Menter DG, Lee MS, Kopetz S. Sorokin AV, et al. Among authors: manyam g. Cancer Res. 2022 Sep 16;82(18):3335-3344. doi: 10.1158/0008-5472.CAN-22-0198. Cancer Res. 2022. PMID: 35913398 Free PMC article.
Autologous humanized mouse models to study combination and single-agent immunotherapy for colorectal cancer patient-derived xenografts.
Kanikarla Marie P, Sorokin AV, Bitner LA, Aden R, Lam M, Manyam G, Woods MN, Anderson A, Capasso A, Fowlkes N, Overman MJ, Menter DG, Kopetz S. Kanikarla Marie P, et al. Among authors: manyam g. Front Oncol. 2022 Sep 21;12:994333. doi: 10.3389/fonc.2022.994333. eCollection 2022. Front Oncol. 2022. PMID: 36212401 Free PMC article.
The consensus molecular subtypes of colorectal cancer.
Guinney J, Dienstmann R, Wang X, de Reyniès A, Schlicker A, Soneson C, Marisa L, Roepman P, Nyamundanda G, Angelino P, Bot BM, Morris JS, Simon IM, Gerster S, Fessler E, De Sousa E Melo F, Missiaglia E, Ramay H, Barras D, Homicsko K, Maru D, Manyam GC, Broom B, Boige V, Perez-Villamil B, Laderas T, Salazar R, Gray JW, Hanahan D, Tabernero J, Bernards R, Friend SH, Laurent-Puig P, Medema JP, Sadanandam A, Wessels L, Delorenzi M, Kopetz S, Vermeulen L, Tejpar S. Guinney J, et al. Among authors: manyam gc. Nat Med. 2015 Nov;21(11):1350-6. doi: 10.1038/nm.3967. Epub 2015 Oct 12. Nat Med. 2015. PMID: 26457759 Free PMC article.
93 results