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Alpha-chemokine receptor blockade reduces high mobility group box 1 protein-induced lung inflammation and injury and improves survival in sepsis.
Lin X, Yang H, Sakuragi T, Hu M, Mantell LL, Hayashi S, Al-Abed Y, Tracey KJ, Ulloa L, Miller EJ. Lin X, et al. Among authors: mantell ll. Am J Physiol Lung Cell Mol Physiol. 2005 Oct;289(4):L583-90. doi: 10.1152/ajplung.00091.2005. Epub 2005 Jun 3. Am J Physiol Lung Cell Mol Physiol. 2005. PMID: 15937067 Free article.
High Mobility Group Box-1 mediates hyperoxia-induced impairment of Pseudomonas aeruginosa clearance and inflammatory lung injury in mice.
Patel VS, Sitapara RA, Gore A, Phan B, Sharma L, Sampat V, Li JH, Yang H, Chavan SS, Wang H, Tracey KJ, Mantell LL. Patel VS, et al. Among authors: mantell ll. Am J Respir Cell Mol Biol. 2013 Mar;48(3):280-7. doi: 10.1165/rcmb.2012-0279OC. Epub 2012 Oct 18. Am J Respir Cell Mol Biol. 2013. PMID: 23087050 Free PMC article.
Inhibition of extracellular HMGB1 attenuates hyperoxia-induced inflammatory acute lung injury.
Entezari M, Javdan M, Antoine DJ, Morrow DM, Sitapara RA, Patel V, Wang M, Sharma L, Gorasiya S, Zur M, Wu W, Li J, Yang H, Ashby CR, Thomas D, Wang H, Mantell LL. Entezari M, et al. Among authors: mantell ll. Redox Biol. 2014 Jan 20;2:314-22. doi: 10.1016/j.redox.2014.01.013. eCollection 2014. Redox Biol. 2014. PMID: 24563849 Free PMC article.
The compromise of macrophage functions by hyperoxia is attenuated by ethacrynic acid via inhibition of NF-κB-mediated release of high-mobility group box-1.
Wang M, Gorasiya S, Antoine DJ, Sitapara RA, Wu W, Sharma L, Yang H, Ashby CR Jr, Vasudevan D, Zur M, Thomas DD, Mantell LL. Wang M, et al. Among authors: mantell ll. Am J Respir Cell Mol Biol. 2015 Feb;52(2):171-82. doi: 10.1165/rcmb.2013-0544OC. Am J Respir Cell Mol Biol. 2015. PMID: 24992505 Free PMC article.
Inhibition of high-mobility group box 1 protein (HMGB1) enhances bacterial clearance and protects against Pseudomonas Aeruginosa pneumonia in cystic fibrosis.
Entezari M, Weiss DJ, Sitapara R, Whittaker L, Wargo MJ, Li J, Wang H, Yang H, Sharma L, Phan BD, Javdan M, Chavan SS, Miller EJ, Tracey KJ, Mantell LL. Entezari M, et al. Among authors: mantell ll. Mol Med. 2012 May 9;18(1):477-85. doi: 10.2119/molmed.2012.00024. Mol Med. 2012. PMID: 22314397 Free PMC article.
56 results