Manninen A - Search Results

1

Biology and Clinical Implications of the 19q13 Aggressive Prostate Cancer Susceptibility Locus.

Gao P, Xia JH, Sipeky C, Dong XM, Zhang Q, Yang Y, Zhang P, Cruz SP, Zhang K, Zhu J, Lee HM, Suleman S, Giannareas N, Liu S; PRACTICAL Consortium; Tammela TLJ, Auvinen A, Wang X, Huang Q, Wang L, Manninen A, Vaarala MH, Wang L, Schleutker J, Wei GH. Gao P, et al. Among authors: manninen a. Cell. 2018 Jul 26;174(3):576-589.e18. doi: 10.1016/j.cell.2018.06.003. Epub 2018 Jul 19. Cell. 2018. PMID: 30033361 Free PMC article.

2

A prostate cancer susceptibility allele at 6q22 increases RFX6 expression by modulating HOXB13 chromatin binding.

Huang Q, Whitington T, Gao P, Lindberg JF, Yang Y, Sun J, Väisänen MR, Szulkin R, Annala M, Yan J, Egevad LA, Zhang K, Lin R, Jolma A, Nykter M, Manninen A, Wiklund F, Vaarala MH, Visakorpi T, Xu J, Taipale J, Wei GH. Huang Q, et al. Among authors: manninen a. Nat Genet. 2014 Feb;46(2):126-35. doi: 10.1038/ng.2862. Epub 2014 Jan 5. Nat Genet. 2014. PMID: 24390282

3

Meta-analysis of gene expression and integrin-associated signaling pathways in papillary renal cell carcinoma subtypes.

Zhang K, Lee HM, Wei GH, Manninen A. Zhang K, et al. Among authors: manninen a. Oncotarget. 2016 Dec 20;7(51):84178-84189. doi: 10.18632/oncotarget.12390. Oncotarget. 2016. PMID: 27705936 Free PMC article.

4

Oncogenic K-Ras upregulates ITGA6 expression via FOSL1 to induce anoikis resistance and synergizes with αV-Class integrins to promote EMT.

Zhang K, Myllymäki SM, Gao P, Devarajan R, Kytölä V, Nykter M, Wei GH, Manninen A. Zhang K, et al. Among authors: manninen a. Oncogene. 2017 Oct 12;36(41):5681-5694. doi: 10.1038/onc.2017.177. Epub 2017 Jun 12. Oncogene. 2017. PMID: 28604746 Free PMC article.

5

Assembly of the β4-Integrin Interactome Based on Proximal Biotinylation in the Presence and Absence of Heterodimerization.

Myllymäki SM, Kämäräinen UR, Liu X, Cruz SP, Miettinen S, Vuorela M, Varjosalo M, Manninen A. Myllymäki SM, et al. Among authors: manninen a. Mol Cell Proteomics. 2019 Feb;18(2):277-293. doi: 10.1074/mcp.RA118.001095. Epub 2018 Nov 7. Mol Cell Proteomics. 2019. PMID: 30404858 Free PMC article.

6

3D Cell Culture Models of Epithelial Tissues.

Zhang K, Manninen A. Zhang K, et al. Among authors: manninen a. Methods Mol Biol. 2019;1926:77-84. doi: 10.1007/978-1-4939-9021-4_7. Methods Mol Biol. 2019. PMID: 30742264

7

Disassembly of α6β4-mediated hemidesmosomal adhesions promotes tumorigenesis in PTEN-negative prostate cancer by targeting plectin to focal adhesions.

Wenta T, Schmidt A, Zhang Q, Devarajan R, Singh P, Yang X, Ahtikoski A, Vaarala M, Wei GH, Manninen A. Wenta T, et al. Among authors: manninen a. Oncogene. 2022 Jul;41(30):3804-3820. doi: 10.1038/s41388-022-02389-5. Epub 2022 Jul 1. Oncogene. 2022. PMID: 35773413 Free PMC article.

8

Extensive germline-somatic interplay contributes to prostate cancer progression through HNF1B co-option of TMPRSS2-ERG.

Giannareas N, Zhang Q, Yang X, Na R, Tian Y, Yang Y, Ruan X, Huang D, Yang X, Wang C, Zhang P, Manninen A, Wang L, Wei GH. Giannareas N, et al. Among authors: manninen a. Nat Commun. 2022 Nov 28;13(1):7320. doi: 10.1038/s41467-022-34994-z. Nat Commun. 2022. PMID: 36443337 Free PMC article.

9

GATA2 co-opts TGFβ1/SMAD4 oncogenic signaling and inherited variants at 6q22 to modulate prostate cancer progression.

Yang X, Zhang Q, Li S, Devarajan R, Luo B, Tan Z, Wang Z, Giannareas N, Wenta T, Ma W, Li Y, Yang Y, Manninen A, Wu S, Wei GH. Yang X, et al. Among authors: manninen a. J Exp Clin Cancer Res. 2023 Aug 8;42(1):198. doi: 10.1186/s13046-023-02745-7. J Exp Clin Cancer Res. 2023. PMID: 37550764 Free PMC article.

10

Dampened Regulatory Circuitry of TEAD1/ITGA1/ITGA2 Promotes TGFβ1 Signaling to Orchestrate Prostate Cancer Progression.

Cruz SP, Zhang Q, Devarajan R, Paia C, Luo B, Zhang K, Koivusalo S, Qin L, Xia J, Ahtikoski A, Vaarala M, Wenta T, Wei GH, Manninen A. Cruz SP, et al. Among authors: manninen a. Adv Sci (Weinh). 2024 Mar;11(11):e2305547. doi: 10.1002/advs.202305547. Epub 2024 Jan 2. Adv Sci (Weinh). 2024. PMID: 38169150 Free PMC article.

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