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Calcium channel β3 subunit regulates ATP-dependent migration of dendritic cells.
Woo MS, Ufer F, Sonner JK, Belkacemi A, Tintelnot J, Sáez PJ, Krieg PF, Mayer C, Binkle-Ladisch L, Engler JB, Bauer S, Kursawe N, Vieira V, Mannebach S, Freichel M, Flockerzi V, Vargas P, Friese MA. Woo MS, et al. Among authors: mannebach s. Sci Adv. 2023 Sep 22;9(38):eadh1653. doi: 10.1126/sciadv.adh1653. Epub 2023 Sep 20. Sci Adv. 2023. PMID: 37729408 Free PMC article.
A background Ca2+ entry pathway mediated by TRPC1/TRPC4 is critical for development of pathological cardiac remodelling.
Camacho Londoño JE, Tian Q, Hammer K, Schröder L, Camacho Londoño J, Reil JC, He T, Oberhofer M, Mannebach S, Mathar I, Philipp SE, Tabellion W, Schweda F, Dietrich A, Kaestner L, Laufs U, Birnbaumer L, Flockerzi V, Freichel M, Lipp P. Camacho Londoño JE, et al. Among authors: mannebach s. Eur Heart J. 2015 Sep 1;36(33):2257-66. doi: 10.1093/eurheartj/ehv250. Epub 2015 Jun 11. Eur Heart J. 2015. PMID: 26069213 Free PMC article.
OCaR1 endows exocytic vesicles with autoregulatory competence by preventing uncontrolled Ca2+ release, exocytosis, and pancreatic tissue damage.
Tsvilovskyy V, Ottenheijm R, Kriebs U, Schütz A, Diakopoulos KN, Jha A, Bildl W, Wirth A, Böck J, Jaślan D, Ferro I, Taberner FJ, Kalinina O, Hildebrand S, Wissenbach U, Weissgerber P, Vogt D, Eberhagen C, Mannebach S, Berlin M, Kuryshev V, Schumacher D, Philippaert K, Camacho-Londoño JE, Mathar I, Dieterich C, Klugbauer N, Biel M, Wahl-Schott C, Lipp P, Flockerzi V, Zischka H, Algül H, Lechner SG, Lesina M, Grimm C, Fakler B, Schulte U, Muallem S, Freichel M. Tsvilovskyy V, et al. Among authors: mannebach s. J Clin Invest. 2024 Apr 1;134(7):e169428. doi: 10.1172/JCI169428. J Clin Invest. 2024. PMID: 38557489 Free PMC article.
Excision of Trpv6 gene leads to severe defects in epididymal Ca2+ absorption and male fertility much like single D541A pore mutation.
Weissgerber P, Kriebs U, Tsvilovskyy V, Olausson J, Kretz O, Stoerger C, Mannebach S, Wissenbach U, Vennekens R, Middendorff R, Flockerzi V, Freichel M. Weissgerber P, et al. Among authors: mannebach s. J Biol Chem. 2012 May 25;287(22):17930-41. doi: 10.1074/jbc.M111.328286. Epub 2012 Mar 15. J Biol Chem. 2012. PMID: 22427671 Free PMC article.
Cytotoxic granule endocytosis depends on the Flower protein.
Chang HF, Mannebach S, Beck A, Ravichandran K, Krause E, Frohnweiler K, Fecher-Trost C, Schirra C, Pattu V, Flockerzi V, Rettig J. Chang HF, et al. Among authors: mannebach s. J Cell Biol. 2018 Feb 5;217(2):667-683. doi: 10.1083/jcb.201706053. Epub 2017 Dec 29. J Cell Biol. 2018. PMID: 29288152 Free PMC article.
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