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Page 1
CXCR2 inhibition enables NASH-HCC immunotherapy.
Leslie J, Mackey JBG, Jamieson T, Ramon-Gil E, Drake TM, Fercoq F, Clark W, Gilroy K, Hedley A, Nixon C, Luli S, Laszczewska M, Pinyol R, Esteban-Fabró R, Willoughby CE, Haber PK, Andreu-Oller C, Rahbari M, Fan C, Pfister D, Raman S, Wilson N, Müller M, Collins A, Geh D, Fuller A, McDonald D, Hulme G, Filby A, Cortes-Lavaud X, Mohamed NE, Ford CA, Raffo Iraolagoitia XL, McFarlane AJ, McCain MV, Ridgway RA, Roberts EW, Barry ST, Graham GJ, Heikenwälder M, Reeves HL, Llovet JM, Carlin LM, Bird TG, Sansom OJ, Mann DA. Leslie J, et al. Among authors: mann da. Gut. 2022 Apr 27;71(10):2093-106. doi: 10.1136/gutjnl-2021-326259. Online ahead of print. Gut. 2022. PMID: 35477863 Free PMC article.
A Proof-of-Concept for Epigenetic Therapy of Tissue Fibrosis: Inhibition of Liver Fibrosis Progression by 3-Deazaneplanocin A.
Zeybel M, Luli S, Sabater L, Hardy T, Oakley F, Leslie J, Page A, Moran Salvador E, Sharkey V, Tsukamoto H, Chu DCK, Singh US, Ponzoni M, Perri P, Di Paolo D, Mendivil EJ, Mann J, Mann DA. Zeybel M, et al. Among authors: mann j, mann da. Mol Ther. 2017 Jan 4;25(1):218-231. doi: 10.1016/j.ymthe.2016.10.004. Epub 2017 Jan 4. Mol Ther. 2017. PMID: 28129116 Free PMC article.
Neutrophils: driving progression and poor prognosis in hepatocellular carcinoma?
Margetts J, Ogle LF, Chan SL, Chan AWH, Chan KCA, Jamieson D, Willoughby CE, Mann DA, Wilson CL, Manas DM, Yeo W, Reeves HL. Margetts J, et al. Among authors: mann da. Br J Cancer. 2018 Jan;118(2):248-257. doi: 10.1038/bjc.2017.386. Epub 2017 Nov 9. Br J Cancer. 2018. PMID: 29123264 Free PMC article.
Non-parenchymal TREM-2 protects the liver from immune-mediated hepatocellular damage.
Perugorria MJ, Esparza-Baquer A, Oakley F, Labiano I, Korosec A, Jais A, Mann J, Tiniakos D, Santos-Laso A, Arbelaiz A, Gawish R, Sampedro A, Fontanellas A, Hijona E, Jimenez-Agüero R, Esterbauer H, Stoiber D, Bujanda L, Banales JM, Knapp S, Sharif O, Mann DA. Perugorria MJ, et al. Among authors: mann j, mann da. Gut. 2019 Mar;68(3):533-546. doi: 10.1136/gutjnl-2017-314107. Epub 2018 Jan 27. Gut. 2019. PMID: 29374630 Free PMC article.
Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer.
Malehmir M, Pfister D, Gallage S, Szydlowska M, Inverso D, Kotsiliti E, Leone V, Peiseler M, Surewaard BGJ, Rath D, Ali A, Wolf MJ, Drescher H, Healy ME, Dauch D, Kroy D, Krenkel O, Kohlhepp M, Engleitner T, Olkus A, Sijmonsma T, Volz J, Deppermann C, Stegner D, Helbling P, Nombela-Arrieta C, Rafiei A, Hinterleitner M, Rall M, Baku F, Borst O, Wilson CL, Leslie J, O'Connor T, Weston CJ, Chauhan A, Adams DH, Sheriff L, Teijeiro A, Prinz M, Bogeska R, Anstee N, Bongers MN, Notohamiprodjo M, Geisler T, Withers DJ, Ware J, Mann DA, Augustin HG, Vegiopoulos A, Milsom MD, Rose AJ, Lalor PF, Llovet JM, Pinyol R, Tacke F, Rad R, Matter M, Djouder N, Kubes P, Knolle PA, Unger K, Zender L, Nieswandt B, Gawaz M, Weber A, Heikenwalder M. Malehmir M, et al. Among authors: mann da. Nat Med. 2019 Apr;25(4):641-655. doi: 10.1038/s41591-019-0379-5. Epub 2019 Apr 1. Nat Med. 2019. PMID: 30936549 Free article.
Fibrogenic Activity of MECP2 Is Regulated by Phosphorylation in Hepatic Stellate Cells.
Moran-Salvador E, Garcia-Macia M, Sivaharan A, Sabater L, Zaki MYW, Oakley F, Knox A, Page A, Luli S, Mann J, Mann DA. Moran-Salvador E, et al. Among authors: mann j, mann da. Gastroenterology. 2019 Nov;157(5):1398-1412.e9. doi: 10.1053/j.gastro.2019.07.029. Epub 2019 Jul 25. Gastroenterology. 2019. PMID: 31352003 Free PMC article.
280 results