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A synthetic antibiotic class overcoming bacterial multidrug resistance.
Mitcheltree MJ, Pisipati A, Syroegin EA, Silvestre KJ, Klepacki D, Mason JD, Terwilliger DW, Testolin G, Pote AR, Wu KJY, Ladley RP, Chatman K, Mankin AS, Polikanov YS, Myers AG. Mitcheltree MJ, et al. Among authors: mankin as. Nature. 2021 Nov;599(7885):507-512. doi: 10.1038/s41586-021-04045-6. Epub 2021 Oct 27. Nature. 2021. PMID: 34707295 Free PMC article.
Selection of small peptides, inhibitors of translation.
Llano-Sotelo B, Klepacki D, Mankin AS. Llano-Sotelo B, et al. Among authors: mankin as. J Mol Biol. 2009 Sep 4;391(5):813-9. doi: 10.1016/j.jmb.2009.06.069. Epub 2009 Jul 2. J Mol Biol. 2009. PMID: 19576904 Free PMC article.
The structure of ribosome-lankacidin complex reveals ribosomal sites for synergistic antibiotics.
Auerbach T, Mermershtain I, Davidovich C, Bashan A, Belousoff M, Wekselman I, Zimmerman E, Xiong L, Klepacki D, Arakawa K, Kinashi H, Mankin AS, Yonath A. Auerbach T, et al. Among authors: mankin as. Proc Natl Acad Sci U S A. 2010 Feb 2;107(5):1983-8. doi: 10.1073/pnas.0914100107. Epub 2010 Jan 11. Proc Natl Acad Sci U S A. 2010. PMID: 20080686 Free PMC article.
Low fitness cost of the multidrug resistance gene cfr.
LaMarre JM, Locke JB, Shaw KJ, Mankin AS. LaMarre JM, et al. Among authors: mankin as. Antimicrob Agents Chemother. 2011 Aug;55(8):3714-9. doi: 10.1128/AAC.00153-11. Epub 2011 Jun 6. Antimicrob Agents Chemother. 2011. PMID: 21646483 Free PMC article.
Role of antibiotic ligand in nascent peptide-dependent ribosome stalling.
Vázquez-Laslop N, Klepacki D, Mulhearn DC, Ramu H, Krasnykh O, Franzblau S, Mankin AS. Vázquez-Laslop N, et al. Among authors: mankin as. Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10496-501. doi: 10.1073/pnas.1103474108. Epub 2011 Jun 13. Proc Natl Acad Sci U S A. 2011. PMID: 21670252 Free PMC article.
162 results