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Development and characterisation of SMURF2-targeting modifiers.
J Enzyme Inhib Med Chem. 2021 Dec;36(1):401-409. doi: 10.1080/14756366.2020.1871337.
J Enzyme Inhib Med Chem. 2021.
PMID: 33430646
Free PMC article.
Generation of SMURF2 knockout human cells using the CRISPR/Cas9 system.
Manikoth Ayyathan D, Ilić N, Gil-Henn H, Blank M.
Manikoth Ayyathan D, et al.
Anal Biochem. 2017 Aug 15;531:56-59. doi: 10.1016/j.ab.2017.05.024. Epub 2017 May 26.
Anal Biochem. 2017.
PMID: 28552759
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Smurf2 regulates stability and the autophagic-lysosomal turnover of lamin A and its disease-associated form progerin.
Borroni AP, Emanuelli A, Shah PA, Ilić N, Apel-Sarid L, Paolini B, Manikoth Ayyathan D, Koganti P, Levy-Cohen G, Blank M.
Borroni AP, et al. Among authors: manikoth ayyathan d.
Aging Cell. 2018 Apr;17(2):e12732. doi: 10.1111/acel.12732. Epub 2018 Feb 5.
Aging Cell. 2018.
PMID: 29405587
Free PMC article.
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The E3 ubiquitin ligase SMURF2 stabilizes RNA editase ADAR1p110 and promotes its adenosine-to-inosine (A-to-I) editing function.
Koganti P, Kadali VN, Manikoth Ayyathan D, Emanuelli A, Paolini B, Levy-Cohen G, Blank M.
Koganti P, et al. Among authors: manikoth ayyathan d.
Cell Mol Life Sci. 2022 Apr 11;79(5):237. doi: 10.1007/s00018-022-04272-8.
Cell Mol Life Sci. 2022.
PMID: 35403872
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SMURF2 prevents detrimental changes to chromatin, protecting human dermal fibroblasts from chromosomal instability and tumorigenesis.
Manikoth Ayyathan D, Koganti P, Marcu-Malina V, Litmanovitch T, Trakhtenbrot L, Emanuelli A, Apel-Sarid L, Blank M.
Manikoth Ayyathan D, et al.
Oncogene. 2020 Apr;39(16):3396-3410. doi: 10.1038/s41388-020-1226-3. Epub 2020 Feb 26.
Oncogene. 2020.
PMID: 32103168
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Altered Expression and Localization of Tumor Suppressive E3 Ubiquitin Ligase SMURF2 in Human Prostate and Breast Cancer.
Emanuelli A, Manikoth Ayyathan D, Koganti P, Shah PA, Apel-Sarid L, Paolini B, Detroja R, Frenkel-Morgenstern M, Blank M.
Emanuelli A, et al. Among authors: manikoth ayyathan d.
Cancers (Basel). 2019 Apr 18;11(4):556. doi: 10.3390/cancers11040556.
Cancers (Basel). 2019.
PMID: 31003445
Free PMC article.
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