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A population study of clinically actionable genetic variation affecting drug response from the Middle East.
Jithesh PV, Abuhaliqa M, Syed N, Ahmed I, El Anbari M, Bastaki K, Sherif S, Umlai UK, Jan Z, Gandhi G, Manickam C, Selvaraj S, George C, Bangarusamy D, Abdel-Latif R, Al-Shafai M, Tatari-Calderone Z, Estivill X, Pirmohamed M; Qatar Genome Program Research Consortium. Jithesh PV, et al. Among authors: manickam c. NPJ Genom Med. 2022 Feb 15;7(1):10. doi: 10.1038/s41525-022-00281-5. NPJ Genom Med. 2022. PMID: 35169154 Free PMC article.
Genetic evaluation of cardiomyopathies in Qatar identifies enrichment of pathogenic sarcomere gene variants and possible founder disease mutations in the Arabs.
Al-Shafai KN, Al-Hashemi M, Manickam C, Musa R, Selvaraj S, Syed N, Vempalli F, Ali M, Yacoub M, Estivill X. Al-Shafai KN, et al. Among authors: manickam c. Mol Genet Genomic Med. 2021 Jul;9(7):e1709. doi: 10.1002/mgg3.1709. Epub 2021 Jun 17. Mol Genet Genomic Med. 2021. PMID: 34137518 Free PMC article.
'FcαRI (CD89) is upregulated on subsets of mucosal and circulating NK cells and regulates IgA-class specific signaling and functions.
Kroll KW, Hueber B, Balachandran H, Afifi A, Manickam C, Nettere D, Pollara J, Hudson A, Woolley G, Ndhlovu LC, Keith Reeves R. Kroll KW, et al. Among authors: manickam c. Mucosal Immunol. 2024 Apr 25:S1933-0219(24)00040-0. doi: 10.1016/j.mucimm.2024.04.003. Online ahead of print. Mucosal Immunol. 2024. PMID: 38677592 Free article.
Multiplex interrogation of the NK cell signalome reveals global downregulation of CD16 signaling during lentivirus infection through an IL-18/ADAM17-dependent mechanism.
Sugawara S, Hueber B, Woolley G, Terry K, Kroll K, Manickam C, Ram DR, Ndhlovu LC, Goepfert P, Jost S, Reeves RK. Sugawara S, et al. Among authors: manickam c. PLoS Pathog. 2023 Sep 5;19(9):e1011629. doi: 10.1371/journal.ppat.1011629. eCollection 2023 Sep. PLoS Pathog. 2023. PMID: 37669308 Free PMC article.
NK cell education: Physiological and pathological influences.
Rascle P, Woolley G, Jost S, Manickam C, Reeves RK. Rascle P, et al. Among authors: manickam c. Front Immunol. 2023 Jan 20;14:1087155. doi: 10.3389/fimmu.2023.1087155. eCollection 2023. Front Immunol. 2023. PMID: 36742337 Free PMC article. Review.
A genetically engineered, stem-cell-derived cellular vaccine.
Cooper A, Sidaway A, Chandrashekar A, Latta E, Chakraborty K, Yu J, McMahan K, Giffin V, Manickam C, Kroll K, Mosher M, Reeves RK, Gam R, Arthofer E, Choudhry M, Henley T, Barouch DH. Cooper A, et al. Among authors: manickam c. Cell Rep Med. 2022 Dec 20;3(12):100843. doi: 10.1016/j.xcrm.2022.100843. Epub 2022 Dec 7. Cell Rep Med. 2022. PMID: 36480934 Free PMC article.
47 results