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The gut metabolite indole-3 propionate promotes nerve regeneration and repair.
Serger E, Luengo-Gutierrez L, Chadwick JS, Kong G, Zhou L, Crawford G, Danzi MC, Myridakis A, Brandis A, Bello AT, Müller F, Sanchez-Vassopoulos A, De Virgiliis F, Liddell P, Dumas ME, Strid J, Mani S, Dodd D, Di Giovanni S. Serger E, et al. Among authors: mani s. Nature. 2022 Jul;607(7919):585-592. doi: 10.1038/s41586-022-04884-x. Epub 2022 Jun 22. Nature. 2022. PMID: 35732737
Symbiotic bacterial metabolites regulate gastrointestinal barrier function via the xenobiotic sensor PXR and Toll-like receptor 4.
Venkatesh M, Mukherjee S, Wang H, Li H, Sun K, Benechet AP, Qiu Z, Maher L, Redinbo MR, Phillips RS, Fleet JC, Kortagere S, Mukherjee P, Fasano A, Le Ven J, Nicholson JK, Dumas ME, Khanna KM, Mani S. Venkatesh M, et al. Among authors: mani s. Immunity. 2014 Aug 21;41(2):296-310. doi: 10.1016/j.immuni.2014.06.014. Epub 2014 Jul 24. Immunity. 2014. PMID: 25065623 Free PMC article.
Microbial control of intestinal innate immunity.
Brave M, Lukin DJ, Mani S. Brave M, et al. Among authors: mani s. Oncotarget. 2015 Aug 21;6(24):19962-3. doi: 10.18632/oncotarget.4780. Oncotarget. 2015. PMID: 26172839 Free PMC article. No abstract available.
The pregnane X receptor and its microbiota-derived ligand indole 3-propionic acid regulate endothelium-dependent vasodilation.
Pulakazhi Venu VK, Saifeddine M, Mihara K, Tsai YC, Nieves K, Alston L, Mani S, McCoy KD, Hollenberg MD, Hirota SA. Pulakazhi Venu VK, et al. Among authors: mani s. Am J Physiol Endocrinol Metab. 2019 Aug 1;317(2):E350-E361. doi: 10.1152/ajpendo.00572.2018. Epub 2019 Jun 18. Am J Physiol Endocrinol Metab. 2019. PMID: 31211619 Free PMC article.
Monoterpenoid aryl hydrocarbon receptor allosteric antagonists protect against ultraviolet skin damage in female mice.
Ondrová K, Zůvalová I, Vyhlídalová B, Krasulová K, Miková E, Vrzal R, Nádvorník P, Nepal B, Kortagere S, Kopečná M, Kopečný D, Šebela M, Rastinejad F, Pu H, Soural M, Rolfes KM, Haarmann-Stemmann T, Li H, Mani S, Dvořák Z. Ondrová K, et al. Among authors: mani s. Nat Commun. 2023 May 11;14(1):2728. doi: 10.1038/s41467-023-38478-6. Nat Commun. 2023. PMID: 37169746 Free PMC article.
1,120 results