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FDA Approval Summary: Mirvetuximab Soravtansine-Gynx for FRα-Positive, Platinum-Resistant Ovarian Cancer.
Dilawari A, Shah M, Ison G, Gittleman H, Fiero MH, Shah A, Hamed SS, Qiu J, Yu J, Manheng W, Ricks TK, Pragani R, Arudchandran A, Patel P, Zaman S, Roy A, Kalavar S, Ghosh S, Pierce WF, Rahman NA, Tang S, Mixter BD, Kluetz PG, Pazdur R, Amiri-Kordestani L. Dilawari A, et al. Among authors: manheng w. Clin Cancer Res. 2023 Oct 2;29(19):3835-3840. doi: 10.1158/1078-0432.CCR-23-0991. Clin Cancer Res. 2023. PMID: 37212825 Free PMC article.
Evaluation of skin sensitization induced by four ionic liquids.
Frawley RP, Germolec DR, Johnson VJ, Gulledge T, Manheng W, White K Jr, Shockley KR, Harris SF, Hooth M, Ryan K. Frawley RP, et al. Among authors: manheng w. J Appl Toxicol. 2022 Mar;42(3):392-408. doi: 10.1002/jat.4224. Epub 2021 Aug 28. J Appl Toxicol. 2022. PMID: 34453447
Evaluation of 2-methoxy-4-nitroaniline (MNA) in hypersensitivity, 14-day subacute, reproductive, and genotoxicity studies.
Frawley RP, Witt KL, Cunny H, Germolec DR, Jackson-Humbles D, Malarkey D, Shockley KR, Stout M, Travlos G, Buccellato M, Fallacara D, Harris S, Kissling GE, Manheng W, Surh II, White K Jr, Auerbach SS. Frawley RP, et al. Among authors: manheng w. Toxicology. 2020 Aug;441:152474. doi: 10.1016/j.tox.2020.152474. Epub 2020 May 5. Toxicology. 2020. PMID: 32380031 Free PMC article.
FDA Approval Summary: Niraparib for the Maintenance Treatment of Patients with Recurrent Ovarian Cancer in Response to Platinum-Based Chemotherapy.
Ison G, Howie LJ, Amiri-Kordestani L, Zhang L, Tang S, Sridhara R, Pierre V, Charlab R, Ramamoorthy A, Song P, Li F, Yu J, Manheng W, Palmby TR, Ghosh S, Horne HN, Lee EY, Philip R, Dave K, Chen XH, Kelly SL, Janoria KG, Banerjee A, Eradiri O, Dinin J, Goldberg KB, Pierce WF, Ibrahim A, Kluetz PG, Blumenthal GM, Beaver JA, Pazdur R. Ison G, et al. Among authors: manheng w. Clin Cancer Res. 2018 Sep 1;24(17):4066-4071. doi: 10.1158/1078-0432.CCR-18-0042. Epub 2018 Apr 12. Clin Cancer Res. 2018. PMID: 29650751