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Silencing c-Myc translation as a therapeutic strategy through targeting PI3Kδ and CK1ε in hematological malignancies.
Deng C, Lipstein MR, Scotto L, Jirau Serrano XO, Mangone MA, Li S, Vendome J, Hao Y, Xu X, Deng SX, Realubit RB, Tatonetti NP, Karan C, Lentzsch S, Fruman DA, Honig B, Landry DW, O'Connor OA. Deng C, et al. Blood. 2017 Jan 5;129(1):88-99. doi: 10.1182/blood-2016-08-731240. Epub 2016 Oct 26. Blood. 2017. PMID: 27784673 Free PMC article.
Generation of pralatrexate resistant T-cell lymphoma lines reveals two patterns of acquired drug resistance that is overcome with epigenetic modifiers.
Scotto L, Kinahan C, Casadei B, Mangone M, Douglass E, Murty VV, Marchi E, Ma H, George C, Montanari F, Califano A, O'Connor OA. Scotto L, et al. Among authors: mangone m. Genes Chromosomes Cancer. 2020 Nov;59(11):639-651. doi: 10.1002/gcc.22884. Epub 2020 Jul 30. Genes Chromosomes Cancer. 2020. PMID: 32614991 Free PMC article.
Pralatrexate pharmacology and clinical development.
Marchi E, Mangone M, Zullo K, O'Connor OA. Marchi E, et al. Among authors: mangone m. Clin Cancer Res. 2013 Dec 15;19(24):6657-61. doi: 10.1158/1078-0432.CCR-12-2251. Epub 2013 Aug 21. Clin Cancer Res. 2013. PMID: 23965902 Clinical Trial.
Aurora A Kinase Inhibition Selectively Synergizes with Histone Deacetylase Inhibitor through Cytokinesis Failure in T-cell Lymphoma.
Zullo KM, Guo Y, Cooke L, Jirau-Serrano X, Mangone M, Scotto L, Amengual JE, Mao Y, Nandakumar R, Cremers S, Duong J, Mahadevan D, O'Connor OA. Zullo KM, et al. Among authors: mangone m. Clin Cancer Res. 2015 Sep 15;21(18):4097-109. doi: 10.1158/1078-0432.CCR-15-0033. Epub 2015 Apr 15. Clin Cancer Res. 2015. PMID: 25878331 Free PMC article.
A Comprehensive Analysis of 3-UTRs in Caenorhabditis elegans.
Murari E, Meadows D, Cuda N, Mangone M. Murari E, et al. Among authors: mangone m. bioRxiv [Preprint]. 2024 Feb 17:2024.02.15.580525. doi: 10.1101/2024.02.15.580525. bioRxiv. 2024. PMID: 38405729 Free PMC article. Preprint.
140 results