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LINE-1 RNA causes heterochromatin erosion and is a target for amelioration of senescent phenotypes in progeroid syndromes.
Sci Transl Med. 2022 Aug 10;14(657):eabl6057. doi: 10.1126/scitranslmed.abl6057. Epub 2022 Aug 10.
Sci Transl Med. 2022.
PMID: 35947677
New insights into the functional role of retrotransposon dynamics in mammalian somatic cells.
Mangiavacchi A, Liu P, Della Valle F, Orlando V.
Mangiavacchi A, et al.
Cell Mol Life Sci. 2021 Jul;78(13):5245-5256. doi: 10.1007/s00018-021-03851-5. Epub 2021 May 14.
Cell Mol Life Sci. 2021.
PMID: 33990851
Free PMC article.
Review.
Item in Clipboard
The miR-223 host non-coding transcript linc-223 induces IRF4 expression in acute myeloid leukemia by acting as a competing endogenous RNA.
Mangiavacchi A, Sorci M, Masciarelli S, Larivera S, Legnini I, Iosue I, Bozzoni I, Fazi F, Fatica A.
Mangiavacchi A, et al.
Oncotarget. 2016 Sep 13;7(37):60155-60168. doi: 10.18632/oncotarget.11165.
Oncotarget. 2016.
PMID: 27517498
Free PMC article.
Item in Clipboard
The microRNA-26a target E2F7 sustains cell proliferation and inhibits monocytic differentiation of acute myeloid leukemia cells.
Salvatori B, Iosue I, Mangiavacchi A, Loddo G, Padula F, Chiaretti S, Peragine N, Bozzoni I, Fazi F, Fatica A.
Salvatori B, et al. Among authors: mangiavacchi a.
Cell Death Dis. 2012 Oct 25;3(10):e413. doi: 10.1038/cddis.2012.151.
Cell Death Dis. 2012.
PMID: 23096114
Free PMC article.
Item in Clipboard
A feedforward regulatory loop between HuR and the long noncoding RNA linc-MD1 controls early phases of myogenesis.
Legnini I, Morlando M, Mangiavacchi A, Fatica A, Bozzoni I.
Legnini I, et al. Among authors: mangiavacchi a.
Mol Cell. 2014 Feb 6;53(3):506-14. doi: 10.1016/j.molcel.2013.12.012. Epub 2014 Jan 16.
Mol Cell. 2014.
PMID: 24440503
Free PMC article.
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Critical Role of c-Myc in Acute Myeloid Leukemia Involving Direct Regulation of miR-26a and Histone Methyltransferase EZH2.
Salvatori B, Iosue I, Djodji Damas N, Mangiavacchi A, Chiaretti S, Messina M, Padula F, Guarini A, Bozzoni I, Fazi F, Fatica A.
Salvatori B, et al. Among authors: mangiavacchi a.
Genes Cancer. 2011 May;2(5):585-92. doi: 10.1177/1947601911416357.
Genes Cancer. 2011.
PMID: 21901171
Free PMC article.
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Behind the scenes: How RNA orchestrates the epigenetic regulation of gene expression.
Mangiavacchi A, Morelli G, Orlando V.
Mangiavacchi A, et al.
Front Cell Dev Biol. 2023 Jan 25;11:1123975. doi: 10.3389/fcell.2023.1123975. eCollection 2023.
Front Cell Dev Biol. 2023.
PMID: 36760365
Free PMC article.
Review.
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