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Discovery of novel isothiazole inhibitors of the TrkA kinase: structure-activity relationship, computer modeling, optimization, and identification of highly potent antagonists.
Lippa B, Morris J, Corbett M, Kwan TA, Noe MC, Snow SL, Gant TG, Mangiaracina M, Coffey HA, Foster B, Knauth EA, Wessel MD. Lippa B, et al. Among authors: mangiaracina m. Bioorg Med Chem Lett. 2006 Jul 1;16(13):3444-8. doi: 10.1016/j.bmcl.2006.04.003. Epub 2006 Apr 24. Bioorg Med Chem Lett. 2006. PMID: 16632359