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Page 1
Learning and Memory Impairments in Patients with Minimal Hepatic Encephalopathy are Associated with Structural and Functional Connectivity Alterations in Hippocampus.
García-García R, Cruz-Gómez ÁJ, Urios A, Mangas-Losada A, Forn C, Escudero-García D, Kosenko E, Torregrosa I, Tosca J, Giner-Durán R, Serra MA, Avila C, Belloch V, Felipo V, Montoliu C. García-García R, et al. Among authors: mangas losada a. Sci Rep. 2018 Jun 25;8(1):9664. doi: 10.1038/s41598-018-27978-x. Sci Rep. 2018. PMID: 29941971 Free PMC article.
The PHES battery does not detect all cirrhotic patients with early neurological deficits, which are different in different patients.
Giménez-Garzó C, Garcés JJ, Urios A, Mangas-Losada A, García-García R, González-López O, Giner-Durán R, Escudero-García D, Serra MA, Soria E, Felipo V, Montoliu C. Giménez-Garzó C, et al. Among authors: mangas losada a. PLoS One. 2017 Feb 1;12(2):e0171211. doi: 10.1371/journal.pone.0171211. eCollection 2017. PLoS One. 2017. PMID: 28146589 Free PMC article.
Reduced resting state connectivity and gray matter volume correlate with cognitive impairment in minimal hepatic encephalopathy.
García-García R, Cruz-Gómez ÁJ, Mangas-Losada A, Urios A, Forn C, Escudero-García D, Kosenko E, Ordoño JF, Tosca J, Giner-Durán R, Serra MA, Avila C, Belloch V, Felipo V, Montoliu C. García-García R, et al. Among authors: mangas losada a. PLoS One. 2017 Oct 12;12(10):e0186463. doi: 10.1371/journal.pone.0186463. eCollection 2017. PLoS One. 2017. PMID: 29023586 Free PMC article.
Cirrhotic patients with minimal hepatic encephalopathy have increased capacity to eliminate superoxide and peroxynitrite in lymphocytes, associated with cognitive impairment.
Giménez-Garzó C, Urios A, Agustí A, Mangas-Losada A, García-García R, Escudero-García D, Kosenko E, Ordoño JF, Tosca J, Giner-Durán R, Serra MA, Felipo V, Montoliu C. Giménez-Garzó C, et al. Among authors: mangas losada a. Free Radic Res. 2018 Jan;52(1):118-133. doi: 10.1080/10715762.2017.1420183. Free Radic Res. 2018. PMID: 29262736
Selective improvement by rifaximin of changes in the immunophenotype in patients who improve minimal hepatic encephalopathy.
Mangas-Losada A, García-García R, Leone P, Ballester MP, Cabrera-Pastor A, Urios A, Gallego JJ, Martínez-Pretel JJ, Giménez-Garzó C, Revert F, Escudero-García D, Tosca J, Ríos MP, Montón C, Durbán L, Aparicio L, Montoliu C, Felipo V. Mangas-Losada A, et al. J Transl Med. 2019 Aug 28;17(1):293. doi: 10.1186/s12967-019-2046-5. J Transl Med. 2019. PMID: 31462286 Free PMC article. Clinical Trial.
Tadalafil Treatment Improves Inflammation, Cognitive Function, And Mismatch Negativity Of Patients With Low Urinary Tract Symptoms And Erectile Dysfunction.
Urios A, Ordoño F, García-García R, Mangas-Losada A, Leone P, José Gallego J, Cabrera-Pastor A, Megías J, Fermin Ordoño J, Felipo V, Montoliu C. Urios A, et al. Among authors: mangas losada a. Sci Rep. 2019 Nov 19;9(1):17119. doi: 10.1038/s41598-019-53136-y. Sci Rep. 2019. PMID: 31745217 Free PMC article.
Peripheral inflammation induces neuroinflammation that alters neurotransmission and cognitive and motor function in hepatic encephalopathy: Underlying mechanisms and therapeutic implications.
Cabrera-Pastor A, Llansola M, Montoliu C, Malaguarnera M, Balzano T, Taoro-Gonzalez L, García-García R, Mangas-Losada A, Izquierdo-Altarejos P, Arenas YM, Leone P, Felipo V. Cabrera-Pastor A, et al. Among authors: mangas losada a. Acta Physiol (Oxf). 2019 Jun;226(2):e13270. doi: 10.1111/apha.13270. Epub 2019 Mar 22. Acta Physiol (Oxf). 2019. PMID: 30830722 Review.