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Sequential or Simultaneous Injection of Preformed Fibrils and AAV Overexpression of Alpha-Synuclein Are Equipotent in Producing Relevant Pathology and Behavioral Deficits.
Negrini M, Tomasello G, Davidsson M, Fenyi A, Adant C, Hauser S, Espa E, Gubinelli F, Manfredsson FP, Melki R, Heuer A. Negrini M, et al. Among authors: manfredsson fp. J Parkinsons Dis. 2022;12(4):1133-1153. doi: 10.3233/JPD-212555. J Parkinsons Dis. 2022. PMID: 35213388 Free PMC article.
Lateralized deficits after unilateral AAV-vector based overexpression of alpha-synuclein in the midbrain of rats on drug-free behavioral tests.
Gubinelli F, Cazzolla G, Negrini M, Kulacz I, Mehrdadian A, Tomasello G, Venuti C, Sarauskyte L, Jacobs F, Manfredsson FP, Davidsson M, Heuer A. Gubinelli F, et al. Among authors: manfredsson fp. Behav Brain Res. 2022 Jul 5;429:113887. doi: 10.1016/j.bbr.2022.113887. Epub 2022 Apr 8. Behav Brain Res. 2022. PMID: 35405174 Free article.
A comparison of machine learning approaches for the quantification of microglial cells in the brain of mice, rats and non-human primates.
Anwer DM, Gubinelli F, Kurt YA, Sarauskyte L, Jacobs F, Venuti C, Sandoval IM, Yang Y, Stancati J, Mazzocchi M, Brandi E, O'Keeffe G, Steece-Collier K, Li JY, Deierborg T, Manfredsson FP, Davidsson M, Heuer A. Anwer DM, et al. Among authors: manfredsson fp. PLoS One. 2023 May 1;18(5):e0284480. doi: 10.1371/journal.pone.0284480. eCollection 2023. PLoS One. 2023. PMID: 37126506 Free PMC article.
Subthalamic Nucleus Deep Brain Stimulation Does Not Modify the Functional Deficits or Axonopathy Induced by Nigrostriatal α-Synuclein Overexpression.
Fischer DL, Manfredsson FP, Kemp CJ, Cole-Strauss A, Lipton JW, Duffy MF, Polinski NK, Steece-Collier K, Collier TJ, Gombash SE, Buhlinger DJ, Sortwell CE. Fischer DL, et al. Among authors: manfredsson fp. Sci Rep. 2017 Nov 27;7(1):16356. doi: 10.1038/s41598-017-16690-x. Sci Rep. 2017. PMID: 29180681 Free PMC article.
Gene Therapy to Modulate Alpha-Synuclein in Synucleinopathies.
Sandoval IM, Marmion DJ, Meyers KT, Manfredsson FP. Sandoval IM, et al. Among authors: manfredsson fp. J Parkinsons Dis. 2021;11(s2):S189-S197. doi: 10.3233/JPD-212679. J Parkinsons Dis. 2021. PMID: 34092656 Free PMC article. Review.
98 results