Manfredi J - Search Results

1

The p53 C terminus controls site-specific DNA binding and promotes structural changes within the central DNA binding domain.

Laptenko O, Shiff I, Freed-Pastor W, Zupnick A, Mattia M, Freulich E, Shamir I, Kadouri N, Kahan T, Manfredi J, Simon I, Prives C. Laptenko O, et al. Among authors: manfredi j. Mol Cell. 2015 Mar 19;57(6):1034-1046. doi: 10.1016/j.molcel.2015.02.015. Mol Cell. 2015. PMID: 25794615 Free PMC article.

2

Functional consequences of the interactions of the p53 tumor suppressor protein and SV40 large tumor antigen.

Prives C, Bargonetti J, Friedman PN, Manfredi JJ, Wang EH. Prives C, et al. Among authors: manfredi jj. Cold Spring Harb Symp Quant Biol. 1991;56:227-35. doi: 10.1101/sqb.1991.056.01.028. Cold Spring Harb Symp Quant Biol. 1991. PMID: 1668081 No abstract available.

3

Binding of p53 and p105-RB is not sufficient for oncogenic transformation by a hybrid polyomavirus-simian virus 40 large T antigen.

Manfredi JJ, Prives C. Manfredi JJ, et al. J Virol. 1990 Nov;64(11):5250-9. doi: 10.1128/JVI.64.11.5250-5259.1990. J Virol. 1990. PMID: 2214017 Free PMC article.

4

The p53 tumor suppressor protein: meeting review.

Prives C, Manfredi JJ. Prives C, et al. Among authors: manfredi jj. Genes Dev. 1993 Apr;7(4):529-34. doi: 10.1101/gad.7.4.529. Genes Dev. 1993. PMID: 8096197 Free article. No abstract available.

5

The transforming activity of simian virus 40 large tumor antigen.

Manfredi JJ, Prives C. Manfredi JJ, et al. Biochim Biophys Acta. 1994 May 27;1198(1):65-83. doi: 10.1016/0304-419x(94)90006-x. Biochim Biophys Acta. 1994. PMID: 8199196 Review. No abstract available.

6

A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein.

Bargonetti J, Manfredi JJ, Chen X, Marshak DR, Prives C. Bargonetti J, et al. Among authors: manfredi jj. Genes Dev. 1993 Dec;7(12B):2565-74. doi: 10.1101/gad.7.12b.2565. Genes Dev. 1993. PMID: 8276239 Free article.

7

Primary rat cells expressing a hybrid polyomavirus-simian virus 40 large T antigen have altered growth properties.

Manfredi JJ, Prives C. Manfredi JJ, et al. J Virol. 1993 Aug;67(8):4750-9. doi: 10.1128/JVI.67.8.4750-4759.1993. J Virol. 1993. PMID: 8392612 Free PMC article.

We previously reported that a hybrid polyomavirus-SV40 large T antigen, PyT1-521-SVT336-708, binds to both p53 and pRb but does not transform an established rat cell line (J. J. Manfredi and C. Prives, J. Virol. 64:5250-5259, 1990). Here we show that t …

We previously reported that a hybrid polyomavirus-SV40 large T antigen, PyT1-521-SVT336-708, binds to both p53 and pRb but does not transfor …

8

p53 and apoptosis: it's not just in the nucleus anymore.

Manfredi JJ. Manfredi JJ. Mol Cell. 2003 Mar;11(3):552-4. doi: 10.1016/s1097-2765(03)00106-0. Mol Cell. 2003. PMID: 12667439 Free article. Review.

9

Electrophoretic mobility shift analysis of the DNA binding of tumor suppressor gene products.

Thornborrow EC, Maurer M, Manfredi JJ. Thornborrow EC, et al. Among authors: manfredi jj. Methods Mol Biol. 2003;223:87-100. doi: 10.1385/1-59259-329-1:87. Methods Mol Biol. 2003. PMID: 12777722 No abstract available.

10

DNA damage-induced downregulation of Cdc25C is mediated by p53 via two independent mechanisms: one involves direct binding to the cdc25C promoter.

St Clair S, Giono L, Varmeh-Ziaie S, Resnick-Silverman L, Liu WJ, Padi A, Dastidar J, DaCosta A, Mattia M, Manfredi JJ. St Clair S, et al. Among authors: manfredi jj. Mol Cell. 2004 Dec 3;16(5):725-36. doi: 10.1016/j.molcel.2004.11.002. Mol Cell. 2004. PMID: 15574328 Free article.

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