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Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.
Tracy TE, Madero-Pérez J, Swaney DL, Chang TS, Moritz M, Konrad C, Ward ME, Stevenson E, Hüttenhain R, Kauwe G, Mercedes M, Sweetland-Martin L, Chen X, Mok SA, Wong MY, Telpoukhovskaia M, Min SW, Wang C, Sohn PD, Martin J, Zhou Y, Luo W, Trojanowski JQ, Lee VMY, Gong S, Manfredi G, Coppola G, Krogan NJ, Geschwind DH, Gan L. Tracy TE, et al. Among authors: manfredi g. Cell. 2022 Feb 17;185(4):712-728.e14. doi: 10.1016/j.cell.2021.12.041. Epub 2022 Jan 20. Cell. 2022. PMID: 35063084 Free PMC article.
Role of soluble adenylyl cyclase in mitochondria.
Valsecchi F, Konrad C, Manfredi G. Valsecchi F, et al. Among authors: manfredi g. Biochim Biophys Acta. 2014 Dec;1842(12 Pt B):2555-60. doi: 10.1016/j.bbadis.2014.05.035. Epub 2014 Jun 5. Biochim Biophys Acta. 2014. PMID: 24907564 Free PMC article. Review.
Mutant TDP-43 does not impair mitochondrial bioenergetics in vitro and in vivo.
Kawamata H, Peixoto P, Konrad C, Palomo G, Bredvik K, Gerges M, Valsecchi F, Petrucelli L, Ravits JM, Starkov A, Manfredi G. Kawamata H, et al. Among authors: manfredi g. Mol Neurodegener. 2017 May 8;12(1):37. doi: 10.1186/s13024-017-0180-1. Mol Neurodegener. 2017. PMID: 28482850 Free PMC article.
Distinct intracellular sAC-cAMP domains regulate ER Ca2+ signaling and OXPHOS function.
Valsecchi F, Konrad C, D'Aurelio M, Ramos-Espiritu LS, Stepanova A, Burstein SR, Galkin A, Magranè J, Starkov A, Buck J, Levin LR, Manfredi G. Valsecchi F, et al. Among authors: manfredi g. J Cell Sci. 2017 Nov 1;130(21):3713-3727. doi: 10.1242/jcs.206318. Epub 2017 Sep 1. J Cell Sci. 2017. PMID: 28864766 Free PMC article.
Parkin is a disease modifier in the mutant SOD1 mouse model of ALS.
Palomo GM, Granatiero V, Kawamata H, Konrad C, Kim M, Arreguin AJ, Zhao D, Milner TA, Manfredi G. Palomo GM, et al. Among authors: manfredi g. EMBO Mol Med. 2018 Oct;10(10):e8888. doi: 10.15252/emmm.201808888. EMBO Mol Med. 2018. PMID: 30126943 Free PMC article.
494 results