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Hedgehog-induced ZFYVE21 promotes chronic vascular inflammation by activating NLRP3 inflammasomes in T cells.
Jiang B, Wang S, Song G, Jiang Q, Fan M, Fang C, Li X, Soh CL, Manes TD, Cheru N, Qin L, Ren P, Jortner B, Wang Q, Quaranta E, Yoo P, Geirsson A, Davis RP, Tellides G, Pober JS, Jane-Wit D. Jiang B, et al. Among authors: manes td. Sci Signal. 2023 Mar 21;16(777):eabo3406. doi: 10.1126/scisignal.abo3406. Epub 2023 Mar 21. Sci Signal. 2023. PMID: 36943921 Free PMC article.
Multiscale genetic architecture of donor-recipient differences reveals intronic LIMS1 mismatches associated with kidney transplant survival.
Sun Z, Zhang Z, Banu K, Gibson IW, Colvin RB, Yi Z, Zhang W, De Kumar B, Reghuvaran A, Pell J, Manes TD, Djamali A, Gallon L, O'Connell PJ, He JC, Pober JS, Heeger PS, Menon MC. Sun Z, et al. Among authors: manes td. J Clin Invest. 2023 Nov 1;133(21):e170420. doi: 10.1172/JCI170420. J Clin Invest. 2023. PMID: 37676733 Free PMC article.
Progenitor-derived human endothelial cells evade alloimmunity by CRISPR/Cas9-mediated complete ablation of MHC expression.
Merola J, Reschke M, Pierce RW, Qin L, Spindler S, Baltazar T, Manes TD, Lopez-Giraldez F, Li G, Bracaglia LG, Xie C, Kirkiles-Smith N, Saltzman WM, Tietjen GT, Tellides G, Pober JS. Merola J, et al. Among authors: manes td. JCI Insight. 2019 Oct 17;4(20):e129739. doi: 10.1172/jci.insight.129739. JCI Insight. 2019. PMID: 31527312 Free PMC article.
ZFYVE21 is a complement-induced Rab5 effector that activates non-canonical NF-κB via phosphoinosotide remodeling of endosomes.
Fang C, Manes TD, Liu L, Liu K, Qin L, Li G, Tobiasova Z, Kirkiles-Smith NC, Patel M, Merola J, Fu W, Liu R, Xie C, Tietjen GT, Nigrovic PA, Tellides G, Pober JS, Jane-Wit D. Fang C, et al. Among authors: manes td. Nat Commun. 2019 May 21;10(1):2247. doi: 10.1038/s41467-019-10041-2. Nat Commun. 2019. PMID: 31113953 Free PMC article.
Antigen Presentation by Vascular Cells.
Pober JS, Merola J, Liu R, Manes TD. Pober JS, et al. Among authors: manes td. Front Immunol. 2017 Dec 22;8:1907. doi: 10.3389/fimmu.2017.01907. eCollection 2017. Front Immunol. 2017. PMID: 29312357 Free PMC article. Review.
28 results