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Conjugation of curcumin-loaded lipid nanoemulsions with cell-penetrating peptides increases their cellular uptake and enhances the anti-inflammatory effects in endothelial cells.
Simion V, Stan D, Constantinescu CA, Deleanu M, Dragan E, Tucureanu MM, Gan AM, Butoi E, Constantin A, Manduteanu I, Simionescu M, Calin M. Simion V, et al. Among authors: manduteanu i. J Pharm Pharmacol. 2016 Feb;68(2):195-207. doi: 10.1111/jphp.12513. Epub 2016 Jan 8. J Pharm Pharmacol. 2016. PMID: 26748549
Diabetes-induced early molecular and functional changes in aortic heart valves in a murine model of atherosclerosis.
Tucureanu MM, Filippi A, Alexandru N, Ana Constantinescu C, Ciortan L, Macarie R, Vadana M, Voicu G, Frunza S, Nistor D, Simionescu A, Simionescu DT, Georgescu A, Manduteanu I. Tucureanu MM, et al. Among authors: manduteanu i. Diab Vasc Dis Res. 2019 Nov;16(6):562-576. doi: 10.1177/1479164119874469. Epub 2019 Sep 18. Diab Vasc Dis Res. 2019. PMID: 31530180 Free PMC article.
Integrins α4β1 and αVβ3 are Reduced in Endothelial Progenitor Cells from Diabetic Dyslipidemic Mice and May Represent New Targets for Therapy in Aortic Valve Disease.
Filippi A, Constantin A, Alexandru N, Voicu G, Constantinescu CA, Rebleanu D, Fenyo M, Simionescu D, Simionescu A, Manduteanu I, Georgescu A. Filippi A, et al. Among authors: manduteanu i. Cell Transplant. 2020 Jan-Dec;29:963689720946277. doi: 10.1177/0963689720946277. Cell Transplant. 2020. PMID: 32841051 Free PMC article.
High Glucose Induced Changes in Human VEC Phenotype in a 3D Hydrogel Derived From Cell-Free Native Aortic Root.
Cecoltan S, Ciortan L, Macarie RD, Vadana M, Mihaila AC, Tucureanu M, Vlad ML, Droc I, Gherghiceanu M, Simionescu A, Simionescu DT, Butoi E, Manduteanu I. Cecoltan S, et al. Among authors: manduteanu i. Front Cardiovasc Med. 2021 Aug 12;8:714573. doi: 10.3389/fcvm.2021.714573. eCollection 2021. Front Cardiovasc Med. 2021. PMID: 34458339 Free PMC article.
VCAM-1 Targeted Lipopolyplexes as Vehicles for Efficient Delivery of shRNA-Runx2 to Osteoblast-Differentiated Valvular Interstitial Cells; Implications in Calcific Valve Disease Treatment.
Voicu G, Rebleanu D, Mocanu CA, Tanko G, Droc I, Uritu CM, Pinteala M, Manduteanu I, Simionescu M, Calin M. Voicu G, et al. Among authors: manduteanu i. Int J Mol Sci. 2022 Mar 30;23(7):3824. doi: 10.3390/ijms23073824. Int J Mol Sci. 2022. PMID: 35409184 Free PMC article.
56 results