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Endoplasmic Reticulum Chaperone Glucose-Regulated Protein 94 Is Essential for Proinsulin Handling.
Ghiasi SM, Dahlby T, Hede Andersen C, Haataja L, Petersen S, Omar-Hmeadi M, Yang M, Pihl C, Bresson SE, Khilji MS, Klindt K, Cheta O, Perone MJ, Tyrberg B, Prats C, Barg S, Tengholm A, Arvan P, Mandrup-Poulsen T, Marzec MT. Ghiasi SM, et al. Diabetes. 2019 Apr;68(4):747-760. doi: 10.2337/db18-0671. Epub 2019 Jan 22. Diabetes. 2019. PMID: 30670477 Free PMC article.
Glucose- and interleukin-1beta-induced beta-cell apoptosis requires Ca2+ influx and extracellular signal-regulated kinase (ERK) 1/2 activation and is prevented by a sulfonylurea receptor 1/inwardly rectifying K+ channel 6.2 (SUR/Kir6.2) selective potassium channel opener in human islets.
Maedler K, Størling J, Sturis J, Zuellig RA, Spinas GA, Arkhammar PO, Mandrup-Poulsen T, Donath MY. Maedler K, et al. Diabetes. 2004 Jul;53(7):1706-13. doi: 10.2337/diabetes.53.7.1706. Diabetes. 2004. PMID: 15220194
Cytokines and type 1 diabetes: a numbers game.
Grunnet LG, Mandrup-Poulsen T. Grunnet LG, et al. Diabetes. 2011 Mar;60(3):697-9. doi: 10.2337/db10-1782. Diabetes. 2011. PMID: 21357470 Free PMC article. No abstract available.
Effects of gevokizumab on glycemia and inflammatory markers in type 2 diabetes.
Cavelti-Weder C, Babians-Brunner A, Keller C, Stahel MA, Kurz-Levin M, Zayed H, Solinger AM, Mandrup-Poulsen T, Dinarello CA, Donath MY. Cavelti-Weder C, et al. Diabetes Care. 2012 Aug;35(8):1654-62. doi: 10.2337/dc11-2219. Epub 2012 Jun 14. Diabetes Care. 2012. PMID: 22699287 Free PMC article. Clinical Trial.
MicroRNAs as regulators of beta-cell function and dysfunction.
Osmai M, Osmai Y, Bang-Berthelsen CH, Pallesen EM, Vestergaard AL, Novotny GW, Pociot F, Mandrup-Poulsen T. Osmai M, et al. Diabetes Metab Res Rev. 2016 May;32(4):334-49. doi: 10.1002/dmrr.2719. Epub 2015 Nov 11. Diabetes Metab Res Rev. 2016. PMID: 26418758 Review.
305 results