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LRRK2 functions in synaptic vesicle endocytosis through a kinase-dependent mechanism.
Arranz AM, Delbroek L, Van Kolen K, Guimarães MR, Mandemakers W, Daneels G, Matta S, Calafate S, Shaban H, Baatsen P, De Bock PJ, Gevaert K, Vanden Berghe P, Verstreken P, De Strooper B, Moechars D. Arranz AM, et al. Among authors: mandemakers w. J Cell Sci. 2015 Feb 1;128(3):541–52. doi: 10.1242/jcs.158196. J Cell Sci. 2015. PMID: 25501810
LRRK2 controls an EndoA phosphorylation cycle in synaptic endocytosis.
Matta S, Van Kolen K, da Cunha R, van den Bogaart G, Mandemakers W, Miskiewicz K, De Bock PJ, Morais VA, Vilain S, Haddad D, Delbroek L, Swerts J, Chávez-Gutiérrez L, Esposito G, Daneels G, Karran E, Holt M, Gevaert K, Moechars DW, De Strooper B, Verstreken P. Matta S, et al. Among authors: mandemakers w. Neuron. 2012 Sep 20;75(6):1008-21. doi: 10.1016/j.neuron.2012.08.022. Neuron. 2012. PMID: 22998870 Free article.
Development of an enzyme-linked immunosorbent assay for detection of cellular and in vivo LRRK2 S935 phosphorylation.
Delbroek L, Van Kolen K, Steegmans L, da Cunha R, Mandemakers W, Daneels G, De Bock PJ, Zhang J, Gevaert K, De Strooper B, Alessi DR, Verstreken P, Moechars DW. Delbroek L, et al. Among authors: mandemakers w. J Pharm Biomed Anal. 2013 Mar 25;76:49-58. doi: 10.1016/j.jpba.2012.12.002. Epub 2012 Dec 16. J Pharm Biomed Anal. 2013. PMID: 23313773 Free PMC article.
Parkin interacts with Ambra1 to induce mitophagy.
Van Humbeeck C, Cornelissen T, Hofkens H, Mandemakers W, Gevaert K, De Strooper B, Vandenberghe W. Van Humbeeck C, et al. Among authors: mandemakers w. J Neurosci. 2011 Jul 13;31(28):10249-61. doi: 10.1523/JNEUROSCI.1917-11.2011. J Neurosci. 2011. PMID: 21753002 Free PMC article.
47 results