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Heparan Sulfate Proteoglycans Can Promote Opposite Effects on Adhesion and Directional Migration of Different Cancer Cells.
J Med Chem. 2020 Dec 24;63(24):15997-16011. doi: 10.1021/acs.jmedchem.0c01848. Epub 2020 Dec 7.
J Med Chem. 2020.
PMID: 33284606
Insights into the role of sulfated glycans in cancer cell adhesion and migration through use of branched peptide probe.
Brunetti J, Depau L, Falciani C, Gentile M, Mandarini E, Riolo G, Lupetti P, Pini A, Bracci L.
Brunetti J, et al. Among authors: mandarini e.
Sci Rep. 2016 Jun 3;6:27174. doi: 10.1038/srep27174.
Sci Rep. 2016.
PMID: 27255651
Free PMC article.
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The GAG-specific branched peptide NT4 reduces angiogenesis and invasiveness of tumor cells.
Bracci L, Mandarini E, Brunetti J, Depau L, Pini A, Terzuoli L, Scali S, Falciani C.
Bracci L, et al. Among authors: mandarini e.
PLoS One. 2018 Mar 22;13(3):e0194744. doi: 10.1371/journal.pone.0194744. eCollection 2018.
PLoS One. 2018.
PMID: 29566097
Free PMC article.
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Unraveling Heparan Sulfate Proteoglycan Binding Motif for Cancer Cell Selectivity.
Brunetti J, Riolo G, Depau L, Mandarini E, Bernini A, Karousou E, Passi A, Pini A, Bracci L, Falciani C.
Brunetti J, et al. Among authors: mandarini e.
Front Oncol. 2019 Sep 18;9:843. doi: 10.3389/fonc.2019.00843. eCollection 2019.
Front Oncol. 2019.
PMID: 31620357
Free PMC article.
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Endocytosis and Trafficking of Heparan Sulfate Proteoglycans in Triple-Negative Breast Cancer Cells Unraveled with a Polycationic Peptide.
Mandarini E, Tollapi E, Zanchi M, Depau L, Pini A, Brunetti J, Bracci L, Falciani C.
Mandarini E, et al.
Int J Mol Sci. 2020 Nov 5;21(21):8282. doi: 10.3390/ijms21218282.
Int J Mol Sci. 2020.
PMID: 33167372
Free PMC article.
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Coupling to a cancer-selective heparan-sulfate-targeted branched peptide can by-pass breast cancer cell resistance to methotrexate.
Depau L, Brunetti J, Falciani C, Scali S, Riolo G, Mandarini E, Pini A, Bracci L.
Depau L, et al. Among authors: mandarini e.
Oncotarget. 2017 Jul 6;8(44):76141-76152. doi: 10.18632/oncotarget.19056. eCollection 2017 Sep 29.
Oncotarget. 2017.
PMID: 29100299
Free PMC article.
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