Mancini F - Search Results

1

From AChE to BACE1 inhibitors: The role of the amine on the indanone scaffold.

Rampa A, Mancini F, De Simone A, Falchi F, Belluti F, Di Martino RM, Gobbi S, Andrisano V, Tarozzi A, Bartolini M, Cavalli A, Bisi A. Rampa A, et al. Among authors: mancini f. Bioorg Med Chem Lett. 2015 Jul 15;25(14):2804-8. doi: 10.1016/j.bmcl.2015.05.002. Epub 2015 May 9. Bioorg Med Chem Lett. 2015. PMID: 26003339

2

Multi-target-directed coumarin derivatives: hAChE and BACE1 inhibitors as potential anti-Alzheimer compounds.

Piazzi L, Cavalli A, Colizzi F, Belluti F, Bartolini M, Mancini F, Recanatini M, Andrisano V, Rampa A. Piazzi L, et al. Among authors: mancini f. Bioorg Med Chem Lett. 2008 Jan 1;18(1):423-6. doi: 10.1016/j.bmcl.2007.09.100. Epub 2007 Oct 4. Bioorg Med Chem Lett. 2008. PMID: 17998161

3

Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 4. Further investigation on the inner spacer.

Tumiatti V, Milelli A, Minarini A, Rosini M, Bolognesi ML, Micco M, Andrisano V, Bartolini M, Mancini F, Recanatini M, Cavalli A, Melchiorre C. Tumiatti V, et al. Among authors: mancini f. J Med Chem. 2008 Nov 27;51(22):7308-12. doi: 10.1021/jm8009684. J Med Chem. 2008. PMID: 18954037

4

Beta-secretase as a target for Alzheimer's disease drug discovery: an overview of in vitro methods for characterization of inhibitors.

Mancini F, De Simone A, Andrisano V. Mancini F, et al. Anal Bioanal Chem. 2011 Jun;400(7):1979-96. doi: 10.1007/s00216-011-4963-x. Epub 2011 Apr 20. Anal Bioanal Chem. 2011. PMID: 21503735 Review.

5

Synthesis of monomeric derivatives to probe memoquin's bivalent interactions.

Bolognesi ML, Chiriano G, Bartolini M, Mancini F, Bottegoni G, Maestri V, Czvitkovich S, Windisch M, Cavalli A, Minarini A, Rosini M, Tumiatti V, Andrisano V, Melchiorre C. Bolognesi ML, et al. Among authors: mancini f. J Med Chem. 2011 Dec 22;54(24):8299-304. doi: 10.1021/jm200691d. Epub 2011 Nov 23. J Med Chem. 2011. PMID: 22054058

6

Design, synthesis, and biological evaluation of substituted 2,3-dihydro-1H-cyclopenta[b]quinolin-9-ylamine related compounds as fructose-1,6-bisphosphatase inhibitors.

Rosini M, Mancini F, Tarozzi A, Colizzi F, Andrisano V, Bolognesi ML, Hrelia P, Melchiorre C. Rosini M, et al. Among authors: mancini f. Bioorg Med Chem. 2006 Dec 1;14(23):7846-53. doi: 10.1016/j.bmc.2006.07.059. Bioorg Med Chem. 2006. PMID: 16908175

7

Multiwell fluorometric and colorimetric microassays for the evaluation of beta-secretase (BACE-1) inhibitors.

Mancini F, Naldi M, Cavrini V, Andrisano V. Mancini F, et al. Anal Bioanal Chem. 2007 Jul;388(5-6):1175-83. doi: 10.1007/s00216-007-1356-2. Epub 2007 May 31. Anal Bioanal Chem. 2007. PMID: 17541560

8

Development of a liquid chromatographic system with fluorescent detection for beta-secretase immobilized enzyme reactor on-line enzymatic studies.

Mancini F, Andrisano V. Mancini F, et al. J Pharm Biomed Anal. 2010 Jul 8;52(3):355-61. doi: 10.1016/j.jpba.2009.07.012. Epub 2009 Jul 22. J Pharm Biomed Anal. 2010. PMID: 19674859

9

Multi-target strategy to address Alzheimer's disease: design, synthesis and biological evaluation of new tacrine-based dimers.

Rizzo S, Bisi A, Bartolini M, Mancini F, Belluti F, Gobbi S, Andrisano V, Rampa A. Rizzo S, et al. Among authors: mancini f. Eur J Med Chem. 2011 Sep;46(9):4336-43. doi: 10.1016/j.ejmech.2011.07.004. Epub 2011 Jul 8. Eur J Med Chem. 2011. PMID: 21798635

10

Human recombinant beta-secretase immobilized enzyme reactor for fast hits' selection and characterization from a virtual screening library.

De Simone A, Mancini F, Cosconati S, Marinelli L, La Pietra V, Novellino E, Andrisano V. De Simone A, et al. Among authors: mancini f. J Pharm Biomed Anal. 2013 Jan 25;73:131-4. doi: 10.1016/j.jpba.2012.03.006. Epub 2012 Mar 29. J Pharm Biomed Anal. 2013. PMID: 22502908

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