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Mapping the genomic landscape of multidrug resistance in Plasmodium falciparum and its impact on parasite fitness.
Mok S, Yeo T, Hong D, Shears MJ, Ross LS, Ward KE, Dhingra SK, Kanai M, Bridgford JL, Tripathi AK, Mlambo G, Burkhard AY, Ansbro MR, Fairhurst KJ, Gil-Iturbe E, Park H, Rozenberg FD, Kim J, Mancia F, Fairhurst RM, Quick M, Uhlemann AC, Sinnis P, Fidock DA. Mok S, et al. Among authors: mancia f. Sci Adv. 2023 Nov 10;9(45):eadi2364. doi: 10.1126/sciadv.adi2364. Epub 2023 Nov 8. Sci Adv. 2023. PMID: 37939186 Free PMC article.
Structure and drug resistance of the Plasmodium falciparum transporter PfCRT.
Kim J, Tan YZ, Wicht KJ, Erramilli SK, Dhingra SK, Okombo J, Vendome J, Hagenah LM, Giacometti SI, Warren AL, Nosol K, Roepe PD, Potter CS, Carragher B, Kossiakoff AA, Quick M, Fidock DA, Mancia F. Kim J, et al. Among authors: mancia f. Nature. 2019 Dec;576(7786):315-320. doi: 10.1038/s41586-019-1795-x. Epub 2019 Nov 27. Nature. 2019. PMID: 31776516 Free PMC article.
Cryo-electron microscopy analysis of small membrane proteins.
Nygaard R, Kim J, Mancia F. Nygaard R, et al. Among authors: mancia f. Curr Opin Struct Biol. 2020 Oct;64:26-33. doi: 10.1016/j.sbi.2020.05.009. Epub 2020 Jun 27. Curr Opin Struct Biol. 2020. PMID: 32603877 Free PMC article. Review.
Evidence for the early emergence of piperaquine-resistant Plasmodium falciparum malaria and modeling strategies to mitigate resistance.
Small-Saunders JL, Hagenah LM, Wicht KJ, Dhingra SK, Deni I, Kim J, Vendome J, Gil-Iturbe E, Roepe PD, Mehta M, Mancia F, Quick M, Eppstein MJ, Fidock DA. Small-Saunders JL, et al. Among authors: mancia f. PLoS Pathog. 2022 Feb 7;18(2):e1010278. doi: 10.1371/journal.ppat.1010278. eCollection 2022 Feb. PLoS Pathog. 2022. PMID: 35130315 Free PMC article.
Structural and molecular basis of choline uptake into the brain by FLVCR2.
Cater RJ, Mukherjee D, Gil-Iturbe E, Erramilli SK, Chen T, Koo K, Santander N, Reckers A, Kloss B, Gawda T, Choy BC, Zhang Z, Katewa A, Larpthaveesarp A, Huang EJ, Mooney SWJ, Clarke OB, Yee SW, Giacomini KM, Kossiakoff AA, Quick M, Arnold T, Mancia F. Cater RJ, et al. Among authors: mancia f. Nature. 2024 May 1. doi: 10.1038/s41586-024-07326-y. Online ahead of print. Nature. 2024. PMID: 38693257
Structural Basis of WLS/Evi-Mediated Wnt Transport and Secretion.
Nygaard R, Yu J, Kim J, Ross DR, Parisi G, Clarke OB, Virshup DM, Mancia F. Nygaard R, et al. Among authors: mancia f. Cell. 2021 Jan 7;184(1):194-206.e14. doi: 10.1016/j.cell.2020.11.038. Epub 2020 Dec 23. Cell. 2021. PMID: 33357447 Free PMC article.
Structural basis of lipopolysaccharide maturation by the O-antigen ligase.
Ashraf KU, Nygaard R, Vickery ON, Erramilli SK, Herrera CM, McConville TH, Petrou VI, Giacometti SI, Dufrisne MB, Nosol K, Zinkle AP, Graham CLB, Loukeris M, Kloss B, Skorupinska-Tudek K, Swiezewska E, Roper DI, Clarke OB, Uhlemann AC, Kossiakoff AA, Trent MS, Stansfeld PJ, Mancia F. Ashraf KU, et al. Among authors: mancia f. Nature. 2022 Apr;604(7905):371-376. doi: 10.1038/s41586-022-04555-x. Epub 2022 Apr 6. Nature. 2022. PMID: 35388216 Free PMC article.
Structure-based analysis of CysZ-mediated cellular uptake of sulfate.
Assur Sanghai Z, Liu Q, Clarke OB, Belcher-Dufrisne M, Wiriyasermkul P, Giese MH, Leal-Pinto E, Kloss B, Tabuso S, Love J, Punta M, Banerjee S, Rajashankar KR, Rost B, Logothetis D, Quick M, Hendrickson WA, Mancia F. Assur Sanghai Z, et al. Among authors: mancia f. Elife. 2018 May 24;7:e27829. doi: 10.7554/eLife.27829. Elife. 2018. PMID: 29792261 Free PMC article.
71 results