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The salicylate 1,2-dioxygenase from Pseudaminobacter salicylatoxidans DSM 6986T is a bifunctional enzyme that inactivates the mycotoxin ochratoxin A by a novel amidohydrolase activity.
Sánchez-Arroyo A, Plaza-Vinuesa L, Rivas BL, Mancheño JM, Muñoz R. Sánchez-Arroyo A, et al. Among authors: mancheno jm. Int J Biol Macromol. 2023 May 15;237:124230. doi: 10.1016/j.ijbiomac.2023.124230. Epub 2023 Mar 28. Int J Biol Macromol. 2023. PMID: 36990411 Free article.
Biochemical and structural studies of two tetrameric nucleoside 2'-deoxyribosyltransferases from psychrophilic and mesophilic bacteria: Insights into cold-adaptation.
Fernández-Lucas J, Acebrón I, Wu RY, Alfaro Y, Acosta J, Kaminski PA, Arroyo M, Joachimiak A, Nocek BP, De la Mata I, Mancheño JM. Fernández-Lucas J, et al. Among authors: mancheno jm. Int J Biol Macromol. 2021 Dec 1;192:138-150. doi: 10.1016/j.ijbiomac.2021.09.164. Epub 2021 Oct 5. Int J Biol Macromol. 2021. PMID: 34624379 Free article.
A structurally unique Fusobacterium nucleatum tannase provides detoxicant activity against gallotannins and pathogen resistance.
Mancheño JM, Atondo E, Tomás-Cortázar J, Luís Lavín J, Plaza-Vinuesa L, Martín-Ruiz I, Barriales D, Palacios A, Daniel Navo C, Sampedro L, Peña-Cearra A, Ángel Pascual-Itoiz M, Castelo J, Carreras-González A, Castellana D, Pellón A, Delgado S, Ruas-Madiedo P, de Las Rivas B, Abecia L, Muñoz R, Jiménez-Osés G, Anguita J, Rodríguez H. Mancheño JM, et al. Microb Biotechnol. 2022 Feb;15(2):648-667. doi: 10.1111/1751-7915.13732. Epub 2020 Dec 18. Microb Biotechnol. 2022. PMID: 33336898 Free PMC article.
2'-Deoxyribosyltransferase from Leishmania mexicana, an efficient biocatalyst for one-pot, one-step synthesis of nucleosides from poorly soluble purine bases.
Crespo N, Sánchez-Murcia PA, Gago F, Cejudo-Sanches J, Galmes MA, Fernández-Lucas J, Mancheño JM. Crespo N, et al. Among authors: mancheno jm. Appl Microbiol Biotechnol. 2017 Oct;101(19):7187-7200. doi: 10.1007/s00253-017-8450-y. Epub 2017 Aug 7. Appl Microbiol Biotechnol. 2017. PMID: 28785897
94 results