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A Primeval Mechanism of Tolerance to Desiccation Based on Glycolic Acid Saves Neurons in Mammals from Ischemia by Reducing Intracellular Calcium-Mediated Excitotoxicity.
Chovsepian A, Berchtold D, Winek K, Mamrak U, Ramírez Álvarez I, Dening Y, Golubczyk D, Weitbrecht L, Dames C, Aillery M, Fernandez-Sanz C, Gajewski Z, Dieterich M, Janowski M, Falkai P, Walczak P, Plesnila N, Meisel A, Pan-Montojo F. Chovsepian A, et al. Among authors: mamrak u. Adv Sci (Weinh). 2022 Feb;9(4):e2103265. doi: 10.1002/advs.202103265. Epub 2021 Dec 14. Adv Sci (Weinh). 2022. PMID: 34904402 Free PMC article.
Inadequate food and water intake determine mortality following stroke in mice.
Lourbopoulos A, Mamrak U, Roth S, Balbi M, Shrouder J, Liesz A, Hellal F, Plesnila N. Lourbopoulos A, et al. Among authors: mamrak u. J Cereb Blood Flow Metab. 2017 Jun;37(6):2084-2097. doi: 10.1177/0271678X16660986. Epub 2016 Jan 1. J Cereb Blood Flow Metab. 2017. PMID: 27449604 Free PMC article.
Inhalation of nitric oxide prevents ischemic brain damage in experimental stroke by selective dilatation of collateral arterioles.
Terpolilli NA, Kim SW, Thal SC, Kataoka H, Zeisig V, Nitzsche B, Klaesner B, Zhu C, Schwarzmaier S, Meissner L, Mamrak U, Engel DC, Drzezga A, Patel RP, Blomgren K, Barthel H, Boltze J, Kuebler WM, Plesnila N. Terpolilli NA, et al. Among authors: mamrak u. Circ Res. 2012 Mar 2;110(5):727-38. doi: 10.1161/CIRCRESAHA.111.253419. Epub 2011 Dec 29. Circ Res. 2012. PMID: 22207711
AMPK-regulated miRNA-210-3p is activated during ischaemic neuronal injury and modulates PI3K-p70S6K signalling.
Pfeiffer S, Tomašcová A, Mamrak U, Haunsberger SJ, Connolly NMC, Resler A, Düssmann H, Weisová P, Jirström E, D'Orsi B, Chen G, Cremona M, Hennessy BT, Plesnila N, Prehn JHM. Pfeiffer S, et al. Among authors: mamrak u. J Neurochem. 2021 Nov;159(4):710-728. doi: 10.1111/jnc.15347. Epub 2021 Mar 18. J Neurochem. 2021. PMID: 33694332 Free article.
Results of a preclinical randomized controlled multicenter trial (pRCT): Anti-CD49d treatment for acute brain ischemia.
Llovera G, Hofmann K, Roth S, Salas-Pérdomo A, Ferrer-Ferrer M, Perego C, Zanier ER, Mamrak U, Rex A, Party H, Agin V, Fauchon C, Orset C, Haelewyn B, De Simoni MG, Dirnagl U, Grittner U, Planas AM, Plesnila N, Vivien D, Liesz A. Llovera G, et al. Among authors: mamrak u. Sci Transl Med. 2015 Aug 5;7(299):299ra121. doi: 10.1126/scitranslmed.aaa9853. Sci Transl Med. 2015. PMID: 26246166
Inhibition of Drp1 provides neuroprotection in vitro and in vivo.
Grohm J, Kim SW, Mamrak U, Tobaben S, Cassidy-Stone A, Nunnari J, Plesnila N, Culmsee C. Grohm J, et al. Among authors: mamrak u. Cell Death Differ. 2012 Sep;19(9):1446-58. doi: 10.1038/cdd.2012.18. Epub 2012 Mar 2. Cell Death Differ. 2012. PMID: 22388349 Free PMC article.
Inhaled nitric oxide suppresses neuroinflammation in experimental ischemic stroke.
Sienel RI, Mamrak U, Biller J, Roth S, Zellner A, Parakaw T, Khambata RS, Liesz A, Haffner C, Ahluwalia A, Seker BF, Plesnila N. Sienel RI, et al. Among authors: mamrak u. J Neuroinflammation. 2023 Dec 15;20(1):301. doi: 10.1186/s12974-023-02988-3. J Neuroinflammation. 2023. PMID: 38102677 Free PMC article.