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The retinoid signalling molecule, TRIM16, is repressed during squamous cell carcinoma skin carcinogenesis in vivo and reduces skin cancer cell migration in vitro.
Cheung BB, Koach J, Tan O, Kim P, Bell JL, D'andreti C, Sutton S, Malyukova A, Sekyere E, Norris M, Haber M, Kavallaris M, Cunningham AM, Proby C, Leigh I, Wilmott JS, Cooper CL, Halliday GM, Scolyer RA, Marshall GM. Cheung BB, et al. Among authors: malyukova a. J Pathol. 2012 Feb;226(3):451-62. doi: 10.1002/path.2986. Epub 2011 Oct 18. J Pathol. 2012. PMID: 22009481 Free PMC article.
TRIM16 acts as a tumour suppressor by inhibitory effects on cytoplasmic vimentin and nuclear E2F1 in neuroblastoma cells.
Marshall GM, Bell JL, Koach J, Tan O, Kim P, Malyukova A, Thomas W, Sekyere EO, Liu T, Cunningham AM, Tobias V, Norris MD, Haber M, Kavallaris M, Cheung BB. Marshall GM, et al. Among authors: malyukova a. Oncogene. 2010 Nov 18;29(46):6172-83. doi: 10.1038/onc.2010.340. Epub 2010 Aug 23. Oncogene. 2010. PMID: 20729920 Free PMC article.
The histone deacetylase SIRT2 stabilizes Myc oncoproteins.
Liu PY, Xu N, Malyukova A, Scarlett CJ, Sun YT, Zhang XD, Ling D, Su SP, Nelson C, Chang DK, Koach J, Tee AE, Haber M, Norris MD, Toon C, Rooman I, Xue C, Cheung BB, Kumar S, Marshall GM, Biankin AV, Liu T. Liu PY, et al. Among authors: malyukova a. Cell Death Differ. 2013 Mar;20(3):503-14. doi: 10.1038/cdd.2012.147. Epub 2012 Nov 23. Cell Death Differ. 2013. PMID: 23175188 Free PMC article.
CDK-mediated activation of the SCF(FBXO) (28) ubiquitin ligase promotes MYC-driven transcription and tumourigenesis and predicts poor survival in breast cancer.
Cepeda D, Ng HF, Sharifi HR, Mahmoudi S, Cerrato VS, Fredlund E, Magnusson K, Nilsson H, Malyukova A, Rantala J, Klevebring D, Viñals F, Bhaskaran N, Zakaria SM, Rahmanto AS, Grotegut S, Nielsen ML, Szigyarto CA, Sun D, Lerner M, Navani S, Widschwendter M, Uhlén M, Jirström K, Pontén F, Wohlschlegel J, Grandér D, Spruck C, Larsson LG, Sangfelt O. Cepeda D, et al. Among authors: malyukova a. EMBO Mol Med. 2013 Jul;5(7):1067-86. doi: 10.1002/emmm.201202341. Epub 2013 Jun 14. EMBO Mol Med. 2013. PMID: 23776131 Free PMC article.
19 results