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Genetic impairments in folate enzymes increase dependence on dietary choline for phosphatidylcholine production at the expense of betaine synthesis.
Ganz AB, Shields K, Fomin VG, Lopez YS, Mohan S, Lovesky J, Chuang JC, Ganti A, Carrier B, Yan J, Taeswuan S, Cohen VV, Swersky CC, Stover JA, Vitiello GA, Malysheva OV, Mudrak E, Caudill MA. Ganz AB, et al. Among authors: malysheva ov. FASEB J. 2016 Oct;30(10):3321-3333. doi: 10.1096/fj.201500138RR. Epub 2016 Jun 24. FASEB J. 2016. PMID: 27342765 Free PMC article. Clinical Trial.
Folate intake, MTHFR genotype, and sex modulate choline metabolism in mice.
Chew TW, Jiang X, Yan J, Wang W, Lusa AL, Carrier BJ, West AA, Malysheva OV, Brenna JT, Gregory JF 3rd, Caudill MA. Chew TW, et al. Among authors: malysheva ov. J Nutr. 2011 Aug;141(8):1475-81. doi: 10.3945/jn.111.138859. Epub 2011 Jun 22. J Nutr. 2011. PMID: 21697299 Free PMC article.
Pregnancy induces transcriptional activation of the peripheral innate immune system and increases oxidative DNA damage among healthy third trimester pregnant women.
Jiang X, Bar HY, Yan J, West AA, Perry CA, Malysheva OV, Devapatla S, Pressman E, Vermeylen FM, Wells MT, Caudill MA. Jiang X, et al. Among authors: malysheva ov. PLoS One. 2012;7(11):e46736. doi: 10.1371/journal.pone.0046736. Epub 2012 Nov 2. PLoS One. 2012. PMID: 23133592 Free PMC article. Clinical Trial.
92 results