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Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2.
Drayman N, DeMarco JK, Jones KA, Azizi SA, Froggatt HM, Tan K, Maltseva NI, Chen S, Nicolaescu V, Dvorkin S, Furlong K, Kathayat RS, Firpo MR, Mastrodomenico V, Bruce EA, Schmidt MM, Jedrzejczak R, Muñoz-Alía MÁ, Schuster B, Nair V, Han KY, O'Brien A, Tomatsidou A, Meyer B, Vignuzzi M, Missiakas D, Botten JW, Brooke CB, Lee H, Baker SC, Mounce BC, Heaton NS, Severson WE, Palmer KE, Dickinson BC, Joachimiak A, Randall G, Tay S. Drayman N, et al. Among authors: maltseva ni. Science. 2021 Aug 20;373(6557):931-936. doi: 10.1126/science.abg5827. Epub 2021 Jul 20. Science. 2021. PMID: 34285133 Free PMC article.
Cleavable C-terminal His-tag vectors for structure determination.
Eschenfeldt WH, Maltseva N, Stols L, Donnelly MI, Gu M, Nocek B, Tan K, Kim Y, Joachimiak A. Eschenfeldt WH, et al. J Struct Funct Genomics. 2010 Mar;11(1):31-9. doi: 10.1007/s10969-010-9082-y. Epub 2010 Mar 6. J Struct Funct Genomics. 2010. PMID: 20213425 Free PMC article.
High-throughput protein purification and quality assessment for crystallization.
Kim Y, Babnigg G, Jedrzejczak R, Eschenfeldt WH, Li H, Maltseva N, Hatzos-Skintges C, Gu M, Makowska-Grzyska M, Wu R, An H, Chhor G, Joachimiak A. Kim Y, et al. Methods. 2011 Sep;55(1):12-28. doi: 10.1016/j.ymeth.2011.07.010. Epub 2011 Aug 31. Methods. 2011. PMID: 21907284 Free PMC article. Review.
Bacillus anthracis inosine 5'-monophosphate dehydrogenase in action: the first bacterial series of structures of phosphate ion-, substrate-, and product-bound complexes.
Makowska-Grzyska M, Kim Y, Wu R, Wilton R, Gollapalli DR, Wang XK, Zhang R, Jedrzejczak R, Mack JC, Maltseva N, Mulligan R, Binkowski TA, Gornicki P, Kuhn ML, Anderson WF, Hedstrom L, Joachimiak A. Makowska-Grzyska M, et al. Biochemistry. 2012 Aug 7;51(31):6148-63. doi: 10.1021/bi300511w. Epub 2012 Jul 25. Biochemistry. 2012. PMID: 22788966 Free PMC article.
Protein production for structural genomics using E. coli expression.
Makowska-Grzyska M, Kim Y, Maltseva N, Li H, Zhou M, Joachimiak G, Babnigg G, Joachimiak A. Makowska-Grzyska M, et al. Methods Mol Biol. 2014;1140:89-105. doi: 10.1007/978-1-4939-0354-2_7. Methods Mol Biol. 2014. PMID: 24590711 Free PMC article.
A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase.
Wellington S, Nag PP, Michalska K, Johnston SE, Jedrzejczak RP, Kaushik VK, Clatworthy AE, Siddiqi N, McCarren P, Bajrami B, Maltseva NI, Combs S, Fisher SL, Joachimiak A, Schreiber SL, Hung DT. Wellington S, et al. Among authors: maltseva ni. Nat Chem Biol. 2017 Sep;13(9):943-950. doi: 10.1038/nchembio.2420. Epub 2017 Jul 3. Nat Chem Biol. 2017. PMID: 28671682 Free PMC article.
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