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Assessment of Mycobacterium tuberculosis pantothenate kinase vulnerability through target knockdown and mechanistically diverse inhibitors.
Antimicrob Agents Chemother. 2014 Jun;58(6):3312-26. doi: 10.1128/AAC.00140-14. Epub 2014 Mar 31.
Antimicrob Agents Chemother. 2014.
PMID: 24687493
Free PMC article.
Screening, identification, and characterization of mechanistically diverse inhibitors of the Mycobacterium tuberculosis enzyme, pantothenate kinase (CoaA).
Venkatraman J, Bhat J, Solapure SM, Sandesh J, Sarkar D, Aishwarya S, Mukherjee K, Datta S, Malolanarasimhan K, Bandodkar B, Das KS.
Venkatraman J, et al. Among authors: malolanarasimhan k.
J Biomol Screen. 2012 Mar;17(3):293-302. doi: 10.1177/1087057111423069. Epub 2011 Nov 15.
J Biomol Screen. 2012.
PMID: 22086722
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Structural and biochemical characterization of compounds inhibiting Mycobacterium tuberculosis pantothenate kinase.
Björkelid C, Bergfors T, Raichurkar AK, Mukherjee K, Malolanarasimhan K, Bandodkar B, Jones TA.
Björkelid C, et al. Among authors: malolanarasimhan k.
J Biol Chem. 2013 Jun 21;288(25):18260-70. doi: 10.1074/jbc.M113.476473. Epub 2013 May 9.
J Biol Chem. 2013.
PMID: 23661699
Free PMC article.
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Thiazolopyridone ureas as DNA gyrase B inhibitors: optimization of antitubercular activity and efficacy.
Kale RR, Kale MG, Waterson D, Raichurkar A, Hameed SP, Manjunatha MR, Kishore Reddy BK, Malolanarasimhan K, Shinde V, Koushik K, Jena LK, Menasinakai S, Humnabadkar V, Madhavapeddi P, Basavarajappa H, Sharma S, Nandishaiah R, Mahesh Kumar KN, Ganguly S, Ahuja V, Gaonkar S, Naveen Kumar CN, Ogg D, Boriack-Sjodin PA, Sambandamurthy VK, de Sousa SM, Ghorpade SR.
Kale RR, et al. Among authors: malolanarasimhan k.
Bioorg Med Chem Lett. 2014 Feb 1;24(3):870-9. doi: 10.1016/j.bmcl.2013.12.080. Epub 2013 Dec 25.
Bioorg Med Chem Lett. 2014.
PMID: 24405701
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Synthesis and biological study of a flavone acetic acid analogue containing an azido reporting group designed as a multifunctional binding site probe.
Malolanarasimhan K, Lai CC, Kelley JA, Iaccarino L, Reynolds D, Young HA, Marquez VE.
Malolanarasimhan K, et al.
Bioorg Med Chem. 2005 Apr 15;13(8):2717-22. doi: 10.1016/j.bmc.2005.02.035.
Bioorg Med Chem. 2005.
PMID: 15781383
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Conformationally constrained analogues of diacylglycerol (DAG). 27. Modulation of membrane translocation of protein kinase C (PKC) isozymes alpha and delta by diacylglycerol lactones (DAG-lactones) containing rigid-rod acyl groups.
Malolanarasimhan K, Kedei N, Sigano DM, Kelley JA, Lai CC, Lewin NE, Surawski RJ, Pavlyukovets VA, Garfield SH, Wincovitch S, Blumberg PM, Marquez VE.
Malolanarasimhan K, et al.
J Med Chem. 2007 Mar 8;50(5):962-78. doi: 10.1021/jm061289j. Epub 2007 Feb 7.
J Med Chem. 2007.
PMID: 17284021
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Short synthesis of octosyl nucleosides.
Knapp S, Thakur VV, Madduru MR, Malolanarasimhan K, Morriello GJ, Doss GA.
Knapp S, et al. Among authors: malolanarasimhan k.
Org Lett. 2006 Mar 30;8(7):1335-7. doi: 10.1021/ol0600382.
Org Lett. 2006.
PMID: 16562885
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Chemo- and Regioselective Conversion of Epoxides to Carbonyl Compounds in 5 M Lithium Perchlorate-Diethyl Ether Medium.
Sudha R, Malola Narasimhan K, Geetha Saraswathy V, Sankararaman S.
Sudha R, et al.
J Org Chem. 1996 Mar 8;61(5):1877-1879. doi: 10.1021/jo951839d.
J Org Chem. 1996.
PMID: 11667069
No abstract available.
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