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Page 1
Inhibition of the MNK1/2-eIF4E Axis Augments Palbociclib-Mediated Antitumor Activity in Melanoma and Breast Cancer.
Prabhu SA, Moussa O, Gonçalves C, LaPierre JH, Chou H, Huang F, Richard VR, Ferruzo PYM, Guettler EM, Soria-Bretones I, Kirby L, Gagnon N, Su J, Silvester J, Krisna SS, Rose AAN, Sheppard KE, Cescon DW, Mallette FA, Zahedi RP, Borchers CH, Del Rincon SV, Miller WH. Prabhu SA, et al. Among authors: mallette fa. Mol Cancer Ther. 2023 Feb 1;22(2):192-204. doi: 10.1158/1535-7163.MCT-22-0092. Mol Cancer Ther. 2023. PMID: 36722142
JARID2 haploinsufficiency is associated with a clinically distinct neurodevelopmental syndrome.
Verberne EA, Goh S, England J, van Ginkel M, Rafael-Croes L, Maas S, Polstra A, Zarate YA, Bosanko KA, Pechter KB, Bedoukian E, Izumi K, Chaudhry A, Robin NH, Boothe M, Lippa NC, Aggarwal V, De Vivo DC, Lehman A, Study C, Stockler S, Bruel AL, Isidor B, Lemons J, Rodriguez-Buritica DF, Richmond CM, Stark Z, Agrawal PB, Kooy RF, Meuwissen MEC, Koolen DA, Pfundt R, Lieden A, Anderlid BM, Glatz D, Mannens MMAM, Bakshi M, Mallette FA, van Haelst MM, Campeau PM. Verberne EA, et al. Among authors: mallette fa. Genet Med. 2021 Feb;23(2):374-383. doi: 10.1038/s41436-020-00992-z. Epub 2020 Oct 20. Genet Med. 2021. PMID: 33077894 Free article.
SOCS1 links cytokine signaling to p53 and senescence.
Calabrese V, Mallette FA, Deschênes-Simard X, Ramanathan S, Gagnon J, Moores A, Ilangumaran S, Ferbeyre G. Calabrese V, et al. Among authors: mallette fa. Mol Cell. 2009 Dec 11;36(5):754-67. doi: 10.1016/j.molcel.2009.09.044. Mol Cell. 2009. PMID: 20005840 Free article.
Tumor suppressor activity of the ERK/MAPK pathway by promoting selective protein degradation.
Deschênes-Simard X, Gaumont-Leclerc MF, Bourdeau V, Lessard F, Moiseeva O, Forest V, Igelmann S, Mallette FA, Saba-El-Leil MK, Meloche S, Saad F, Mes-Masson AM, Ferbeyre G. Deschênes-Simard X, et al. Among authors: mallette fa. Genes Dev. 2013 Apr 15;27(8):900-15. doi: 10.1101/gad.203984.112. Epub 2013 Apr 18. Genes Dev. 2013. PMID: 23599344 Free PMC article.
ZNF768: controlling cellular senescence and proliferation with ten fingers.
Villot R, Poirier A, Devillers R, Kolnoguz A, Elowe S, Manem VSK, Joubert P, Mallette FA, Laplante M. Villot R, et al. Among authors: mallette fa. Mol Cell Oncol. 2021 Dec 8;8(6):1985930. doi: 10.1080/23723556.2021.1985930. eCollection 2021. Mol Cell Oncol. 2021. PMID: 35419475 Free PMC article.
p16INK4a Regulates Cellular Senescence in PD-1-Expressing Human T Cells.
Janelle V, Neault M, Lebel MÈ, De Sousa DM, Boulet S, Durrieu L, Carli C, Muzac C, Lemieux S, Labrecque N, Melichar HJ, Mallette FA, Delisle JS. Janelle V, et al. Among authors: mallette fa. Front Immunol. 2021 Aug 9;12:698565. doi: 10.3389/fimmu.2021.698565. eCollection 2021. Front Immunol. 2021. PMID: 34434190 Free PMC article.
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