Malkowitz L - Search Results

1

Label-free high-throughput screening via mass spectrometry: a single cystathionine quantitative method for multiple applications.

Holt TG, Choi BK, Geoghagen NS, Jensen KK, Luo Q, LaMarr WA, Makara GM, Malkowitz L, Ozbal CC, Xiong Y, Dufresne C, Luo MJ. Holt TG, et al. Among authors: malkowitz l. Assay Drug Dev Technol. 2009 Oct;7(5):495-506. doi: 10.1089/adt.2009.0200. Assay Drug Dev Technol. 2009. PMID: 19715455

2

Pharmacological activation and genetic manipulation of cystathionine beta-synthase alter circulating levels of homocysteine and hydrogen sulfide in mice.

Jensen KK, Geoghagen NS, Jin L, Holt TG, Luo Q, Malkowitz L, Ni W, Quan S, Waters MG, Zhang A, Zhou HH, Cheng K, Luo MJ. Jensen KK, et al. Among authors: malkowitz l. Eur J Pharmacol. 2011 Jan 10;650(1):86-93. doi: 10.1016/j.ejphar.2010.09.080. Epub 2010 Oct 15. Eur J Pharmacol. 2011. PMID: 20955694

3

11β-HSD1 inhibition reduces atherosclerosis in mice by altering proinflammatory gene expression in the vasculature.

Luo MJ, Thieringer R, Springer MS, Wright SD, Hermanowski-Vosatka A, Plump A, Balkovec JM, Cheng K, Ding GJ, Kawka DW, Koo GC, Grand CB, Luo Q, Maletic MM, Malkowitz L, Shah K, Singer I, Waddell ST, Wu KK, Yuan J, Zhu J, Stepaniants S, Yang X, Lum PY, Wang IM. Luo MJ, et al. Among authors: malkowitz l. Physiol Genomics. 2013 Jan 7;45(1):47-57. doi: 10.1152/physiolgenomics.00109.2012. Epub 2012 Nov 20. Physiol Genomics. 2013. PMID: 23170035

4

Combinatorial synthesis of 3-(amidoalkyl) and 3-(aminoalkyl)-2-arylindole derivatives: discovery of potent ligands for a variety of G-protein coupled receptors.

Willoughby CA, Hutchins SM, Rosauer KG, Dhar MJ, Chapman KT, Chicchi GG, Sadowski S, Weinberg DH, Patel S, Malkowitz L, Di Salvo J, Pacholok SG, Cheng K. Willoughby CA, et al. Among authors: malkowitz l. Bioorg Med Chem Lett. 2002 Jan 7;12(1):93-6. doi: 10.1016/s0960-894x(01)00665-5. Bioorg Med Chem Lett. 2002. PMID: 11738581

5

Combinatorial synthesis of CCR5 antagonists.

Willoughby CA, Berk SC, Rosauer KG, Degrado S, Chapman KT, Gould SL, Springer MS, Malkowitz L, Schleif WA, Hazuda D, Miller M, Kessler J, Danzeisen R, Holmes K, Lineberger J, Carella A, Carver G, Emini EA. Willoughby CA, et al. Among authors: malkowitz l. Bioorg Med Chem Lett. 2001 Dec 17;11(24):3137-41. doi: 10.1016/s0960-894x(01)00652-7. Bioorg Med Chem Lett. 2001. PMID: 11720860

6

CCR5, CXCR4, and CD4 are clustered and closely apposed on microvilli of human macrophages and T cells.

Singer II, Scott S, Kawka DW, Chin J, Daugherty BL, DeMartino JA, DiSalvo J, Gould SL, Lineberger JE, Malkowitz L, Miller MD, Mitnaul L, Siciliano SJ, Staruch MJ, Williams HR, Zweerink HJ, Springer MS. Singer II, et al. Among authors: malkowitz l. J Virol. 2001 Apr;75(8):3779-90. doi: 10.1128/JVI.75.8.3779-3790.2001. J Virol. 2001. PMID: 11264367 Free PMC article.

7

Cloning, expression, and characterization of the human eosinophil eotaxin receptor.

Daugherty BL, Siciliano SJ, DeMartino JA, Malkowitz L, Sirotina A, Springer MS. Daugherty BL, et al. Among authors: malkowitz l. J Exp Med. 1996 May 1;183(5):2349-54. doi: 10.1084/jem.183.5.2349. J Exp Med. 1996. PMID: 8642344 Free PMC article.

8

1,3,4-Trisubstituted pyrrolidine CCR5 receptor antagonists. Part 1: discovery of the pyrrolidine scaffold and determination of its stereochemical requirements.

Hale JJ, Budhu RJ, Mills SG, MacCoss M, Malkowitz L, Siciliano S, Gould SL, DeMartino JA, Springer MS. Hale JJ, et al. Among authors: malkowitz l. Bioorg Med Chem Lett. 2001 Jun 4;11(11):1437-40. doi: 10.1016/s0960-894x(01)00232-3. Bioorg Med Chem Lett. 2001. PMID: 11378372

9

Two-site binding of C5a by its receptor: an alternative binding paradigm for G protein-coupled receptors.

Siciliano SJ, Rollins TE, DeMartino J, Konteatis Z, Malkowitz L, Van Riper G, Bondy S, Rosen H, Springer MS. Siciliano SJ, et al. Among authors: malkowitz l. Proc Natl Acad Sci U S A. 1994 Feb 15;91(4):1214-8. doi: 10.1073/pnas.91.4.1214. Proc Natl Acad Sci U S A. 1994. PMID: 8108389 Free PMC article.

10

CCR5 antagonists: 3-(pyrrolidin-1-yl)propionic acid analogues with potent anti-HIV activity.

Lynch CL, Hale JJ, Budhu RJ, Gentry AL, Finke PE, Caldwell CG, Mills SG, MacCoss M, Shen DM, Chapman KT, Malkowitz L, Springer MS, Gould SL, DeMartino JA, Siciliano SJ, Cascieri MA, Carella A, Carver G, Holmes K, Schleif WA, Danzeisen R, Hazuda D, Kessler J, Lineberger J, Miller M, Emini E. Lynch CL, et al. Among authors: malkowitz l. Org Lett. 2003 Jul 10;5(14):2473-5. doi: 10.1021/ol034707c. Org Lett. 2003. PMID: 12841758

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