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Anatomical structures, cell types and biomarkers of the Human Reference Atlas.
Börner K, Teichmann SA, Quardokus EM, Gee JC, Browne K, Osumi-Sutherland D, Herr BW 2nd, Bueckle A, Paul H, Haniffa M, Jardine L, Bernard A, Ding SL, Miller JA, Lin S, Halushka MK, Boppana A, Longacre TA, Hickey J, Lin Y, Valerius MT, He Y, Pryhuber G, Sun X, Jorgensen M, Radtke AJ, Wasserfall C, Ginty F, Ho J, Sunshine J, Beuschel RT, Brusko M, Lee S, Malhotra R, Jain S, Weber G. Börner K, et al. Among authors: malhotra r. Nat Cell Biol. 2021 Nov;23(11):1117-1128. doi: 10.1038/s41556-021-00788-6. Epub 2021 Nov 8. Nat Cell Biol. 2021. PMID: 34750582 Free PMC article. Review.
HDAC9 is implicated in atherosclerotic aortic calcification and affects vascular smooth muscle cell phenotype.
Malhotra R, Mauer AC, Lino Cardenas CL, Guo X, Yao J, Zhang X, Wunderer F, Smith AV, Wong Q, Pechlivanis S, Hwang SJ, Wang J, Lu L, Nicholson CJ, Shelton G, Buswell MD, Barnes HJ, Sigurslid HH, Slocum C, Rourke CO, Rhee DK, Bagchi A, Nigwekar SU, Buys ES, Campbell CY, Harris T, Budoff M, Criqui MH, Rotter JI, Johnson AD, Song C, Franceschini N, Debette S, Hoffmann U, Kälsch H, Nöthen MM, Sigurdsson S, Freedman BI, Bowden DW, Jöckel KH, Moebus S, Erbel R, Feitosa MF, Gudnason V, Thanassoulis G, Zapol WM, Lindsay ME, Bloch DB, Post WS, O'Donnell CJ. Malhotra R, et al. Nat Genet. 2019 Nov;51(11):1580-1587. doi: 10.1038/s41588-019-0514-8. Epub 2019 Oct 28. Nat Genet. 2019. PMID: 31659325 Free PMC article.
Modulating Cell Fate as a Therapeutic Strategy.
Lin B, Srikanth P, Castle AC, Nigwekar S, Malhotra R, Galloway JL, Sykes DB, Rajagopal J. Lin B, et al. Among authors: malhotra r. Cell Stem Cell. 2018 Sep 6;23(3):329-341. doi: 10.1016/j.stem.2018.05.009. Epub 2018 Jun 14. Cell Stem Cell. 2018. PMID: 29910150 Free PMC article. Review.
Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification.
Kavousi M, Bos MM, Barnes HJ, Lino Cardenas CL, Wong D, Lu H, Hodonsky CJ, Landsmeer LPL, Turner AW, Kho M, Hasbani NR, de Vries PS, Bowden DW, Chopade S, Deelen J, Benavente ED, Guo X, Hofer E, Hwang SJ, Lutz SM, Lyytikäinen LP, Slenders L, Smith AV, Stanislawski MA, van Setten J, Wong Q, Yanek LR, Becker DM, Beekman M, Budoff MJ, Feitosa MF, Finan C, Hilliard AT, Kardia SLR, Kovacic JC, Kral BG, Langefeld CD, Launer LJ, Malik S, Hoesein FAAM, Mokry M, Schmidt R, Smith JA, Taylor KD, Terry JG, van der Grond J, van Meurs J, Vliegenthart R, Xu J, Young KA, Zilhão NR, Zweiker R, Assimes TL, Becker LC, Bos D, Carr JJ, Cupples LA, de Kleijn DPV, de Winther M, den Ruijter HM, Fornage M, Freedman BI, Gudnason V, Hingorani AD, Hokanson JE, Ikram MA, Išgum I, Jacobs DR Jr, Kähönen M, Lange LA, Lehtimäki T, Pasterkamp G, Raitakari OT, Schmidt H, Slagboom PE, Uitterlinden AG, Vernooij MW, Bis JC, Franceschini N, Psaty BM, Post WS, Rotter JI, Björkegren JLM, O'Donnell CJ, Bielak LF, Peyser PA, Malhotra R, van der Laan SW, Miller CL. Kavousi M, et al. Among authors: malhotra r. Nat Genet. 2023 Oct;55(10):1651-1664. doi: 10.1038/s41588-023-01518-4. Epub 2023 Sep 28. Nat Genet. 2023. PMID: 37770635 Free PMC article.
An HDAC9-MALAT1-BRG1 complex mediates smooth muscle dysfunction in thoracic aortic aneurysm.
Lino Cardenas CL, Kessinger CW, Cheng Y, MacDonald C, MacGillivray T, Ghoshhajra B, Huleihel L, Nuri S, Yeri AS, Jaffer FA, Kaminski N, Ellinor P, Weintraub NL, Malhotra R, Isselbacher EM, Lindsay ME. Lino Cardenas CL, et al. Among authors: malhotra r. Nat Commun. 2018 Mar 8;9(1):1009. doi: 10.1038/s41467-018-03394-7. Nat Commun. 2018. PMID: 29520069 Free PMC article.
Case 23-2019: A 52-Year-Old Man with Fever, Cough, and Hypoxemia.
Hardin CC, Malhotra R, Petranović M, Klassen S, Mihatov N, Oakley DH. Hardin CC, et al. Among authors: malhotra r. N Engl J Med. 2019 Jul 25;381(4):359-369. doi: 10.1056/NEJMcpc1900598. N Engl J Med. 2019. PMID: 31340098 No abstract available.
Persistent Iron Deficiency and Dysregulated Hepcidin Levels After Durable Left Ventricular Assist Device Therapy.
Ton VK, Drezek K, Boerboom S, Ostrom KF, Birchenough C, Camuso J, Logan T, Milley K, Anthony A, Thomas SS, Coglianese E, D'Alessandro DD, Malhotra R, Lewis GD. Ton VK, et al. Among authors: malhotra r. ASAIO J. 2023 Apr 1;69(4):e152-e154. doi: 10.1097/MAT.0000000000001811. Epub 2022 Sep 9. ASAIO J. 2023. PMID: 36084293 No abstract available.
1,857 results