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Vascular smooth muscle cell dysfunction contribute to neuroinflammation and Tau hyperphosphorylation in Alzheimer disease.
Aguilar-Pineda JA, Vera-Lopez KJ, Shrivastava P, Chávez-Fumagalli MA, Nieto-Montesinos R, Alvarez-Fernandez KL, Goyzueta Mamani LD, Davila Del-Carpio G, Gomez-Valdez B, Miller CL, Malhotra R, Lindsay ME, Lino Cardenas CL. Aguilar-Pineda JA, et al. Among authors: malhotra r. iScience. 2021 Aug 19;24(9):102993. doi: 10.1016/j.isci.2021.102993. eCollection 2021 Sep 24. iScience. 2021. PMID: 34505007 Free PMC article.
An HDAC9-MALAT1-BRG1 complex mediates smooth muscle dysfunction in thoracic aortic aneurysm.
Lino Cardenas CL, Kessinger CW, Cheng Y, MacDonald C, MacGillivray T, Ghoshhajra B, Huleihel L, Nuri S, Yeri AS, Jaffer FA, Kaminski N, Ellinor P, Weintraub NL, Malhotra R, Isselbacher EM, Lindsay ME. Lino Cardenas CL, et al. Among authors: malhotra r. Nat Commun. 2018 Mar 8;9(1):1009. doi: 10.1038/s41467-018-03394-7. Nat Commun. 2018. PMID: 29520069 Free PMC article.
HDAC9 is implicated in atherosclerotic aortic calcification and affects vascular smooth muscle cell phenotype.
Malhotra R, Mauer AC, Lino Cardenas CL, Guo X, Yao J, Zhang X, Wunderer F, Smith AV, Wong Q, Pechlivanis S, Hwang SJ, Wang J, Lu L, Nicholson CJ, Shelton G, Buswell MD, Barnes HJ, Sigurslid HH, Slocum C, Rourke CO, Rhee DK, Bagchi A, Nigwekar SU, Buys ES, Campbell CY, Harris T, Budoff M, Criqui MH, Rotter JI, Johnson AD, Song C, Franceschini N, Debette S, Hoffmann U, Kälsch H, Nöthen MM, Sigurdsson S, Freedman BI, Bowden DW, Jöckel KH, Moebus S, Erbel R, Feitosa MF, Gudnason V, Thanassoulis G, Zapol WM, Lindsay ME, Bloch DB, Post WS, O'Donnell CJ. Malhotra R, et al. Nat Genet. 2019 Nov;51(11):1580-1587. doi: 10.1038/s41588-019-0514-8. Epub 2019 Oct 28. Nat Genet. 2019. PMID: 31659325 Free PMC article.
The Role of Bone Morphogenetic Protein Signaling in Non-Alcoholic Fatty Liver Disease.
Thayer TE, Lino Cardenas CL, Martyn T, Nicholson CJ, Traeger L, Wunderer F, Slocum C, Sigurslid H, Shakartzi HR, O'Rourke C, Shelton G, Buswell MD, Barnes H, Neitzel LR, Ledsky CD, Li JP, Burke MF, Farber-Eger E, Perrien DS, Kumar R, Corey KE, Wells QS, Bloch KD, Hong CC, Bloch DB, Malhotra R. Thayer TE, et al. Among authors: malhotra r. Sci Rep. 2020 Jun 19;10(1):9831. doi: 10.1038/s41598-020-66770-8. Sci Rep. 2020. PMID: 32561790 Free PMC article.
Structural and functional analysis of female sex hormones against SARS-Cov2 cell entry.
Aguilar-Pineda JA, Albaghdadi M, Jiang W, Lopez KJV, Del-Carpio GD, Valdez BG, Lindsay ME, Malhotra R, Lino Cardenas CL. Aguilar-Pineda JA, et al. Among authors: malhotra r. bioRxiv [Preprint]. 2020 Jul 29:2020.07.29.227249. doi: 10.1101/2020.07.29.227249. bioRxiv. 2020. PMID: 32766583 Free PMC article. Updated. Preprint.
Structural and Functional Analysis of Female Sex Hormones against SARS-CoV-2 Cell Entry.
Aguilar-Pineda JA, Albaghdadi M, Jiang W, Vera-Lopez KJ, Nieto-Montesinos R, Alvarez KLF, Davila Del-Carpio G, Gómez B, Lindsay ME, Malhotra R, Lino Cardenas CL. Aguilar-Pineda JA, et al. Among authors: malhotra r. Int J Mol Sci. 2021 Oct 26;22(21):11508. doi: 10.3390/ijms222111508. Int J Mol Sci. 2021. PMID: 34768939 Free PMC article.
Matrix Gla Protein Levels Are Associated With Arterial Stiffness and Incident Heart Failure With Preserved Ejection Fraction.
Malhotra R, Nicholson CJ, Wang D, Bhambhani V, Paniagua S, Slocum C, Sigurslid HH, Lino Cardenas CL, Li R, Boerboom SL, Chen YC, Hwang SJ, Yao C, Ichinose F, Bloch DB, Lindsay ME, Lewis GD, Aragam JR, Hoffmann U, Mitchell GF, Hamburg NM, Vasan RS, Benjamin EJ, Larson MG, Zapol WM, Cheng S, Roh JD, O'Donnell CJ, Nguyen C, Levy D, Ho JE. Malhotra R, et al. Arterioscler Thromb Vasc Biol. 2022 Feb;42(2):e61-e73. doi: 10.1161/ATVBAHA.121.316664. Epub 2021 Nov 23. Arterioscler Thromb Vasc Biol. 2022. PMID: 34809448 Free PMC article.
FHL5 Controls Vascular Disease-Associated Gene Programs in Smooth Muscle Cells.
Wong D, Auguste G, Lino Cardenas CL, Turner AW, Chen Y, Song Y, Ma L, Perry RN, Aherrahrou R, Kuppusamy M, Yang C, Mosquera JV, Dube CJ, Khan MD, Palmore M, Kalra J, Kavousi M, Peyser PA, Matic L, Hedin U, Manichaikul A, Sonkusare SK, Civelek M, Kovacic JC, Björkegren JLM, Malhotra R, Miller CL. Wong D, et al. Among authors: malhotra r. Circ Res. 2023 Apr 28;132(9):1144-1161. doi: 10.1161/CIRCRESAHA.122.321692. Epub 2023 Apr 5. Circ Res. 2023. PMID: 37017084 Free PMC article.
1,858 results